An Unusual Case of Adult-Onset Still’s Disease with Hemophagocytic Syndrome, Necrotic Leukoencephalopathy and Disseminated Intravascular Coagulation
المؤلفون المشاركون
Levine, Miriam
Venkatram, Malini
Altinok, Gulcin
Nannapaneni, Naveen
Namas, Rajaie
Dhar, J. Patricia
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-04
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Case.
A 34-year-old African-American female with a history of adult-onset Still’s disease presented to an outside hospital with oligoarthritis.
She experienced a generalized tonic-clonic seizure en route via ambulance, was intubated upon arrival, and transferred to the intensive care unit for treatment of suspected pneumonia and sepsis.
She subsequently developed generalized cutaneous desquamation that progressed despite the cessation of antibiotics and other potential offending drugs which required transfer to our hospital’s burn unit.
She was suspected to have reactive hemophagocytic syndrome based on her clinical presentation of fever, rash, polyarthritis, elevated liver enzymes, coagulopathy, splenomegaly, normocytic anemia, thrombocytopenia, hypertriglyceridemia, hyperferritinemia, and hemophagocytosis visualized in bone marrow biopsy specimen.
Magnetic resonance imaging demonstrated necrotic demyelination of the deep white matter and corona radiata.
The patient developed multiorgan dysfunction and DIC without any other attributable etiology.
Despite aggressive broad spectrum therapy and high dose of steroids she progressively deteriorated and eventually expired.
Conclusion.
Previous publications have highlighted the prevalence of necrotic leukoencephalopathy in children with familial hemophagocytic syndrome.
Our patient demonstrated some uncommon features complicating her HLH including DIC and necrotic leukoencephalopathy, which are very rare entities in AOSD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Namas, Rajaie& Nannapaneni, Naveen& Venkatram, Malini& Altinok, Gulcin& Levine, Miriam& Dhar, J. Patricia. 2014. An Unusual Case of Adult-Onset Still’s Disease with Hemophagocytic Syndrome, Necrotic Leukoencephalopathy and Disseminated Intravascular Coagulation. Case Reports in Rheumatology،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1017682
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Namas, Rajaie…[et al.]. An Unusual Case of Adult-Onset Still’s Disease with Hemophagocytic Syndrome, Necrotic Leukoencephalopathy and Disseminated Intravascular Coagulation. Case Reports in Rheumatology No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1017682
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Namas, Rajaie& Nannapaneni, Naveen& Venkatram, Malini& Altinok, Gulcin& Levine, Miriam& Dhar, J. Patricia. An Unusual Case of Adult-Onset Still’s Disease with Hemophagocytic Syndrome, Necrotic Leukoencephalopathy and Disseminated Intravascular Coagulation. Case Reports in Rheumatology. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1017682
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1017682
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر