Evaluating the Individualized Treatment of Traditional Chinese Medicine: A Pilot Study of N-of-1 Trials
المؤلفون المشاركون
Guyatt, Gordon
Zhang, Yuqing
Huang, Haiyin
Yang, Peilan
Xue, Jingjing
Tang, Jie
Ding, Liyu
Ma, Ying
Wang, Jie
Vanniyasingam, Thuva
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-11-11
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Purpose.
To compare the efficacy of individualized herbal decoction with controlled decoction for individual patients with stable bronchiectasis.
Methods.
We conducted N-of-1 RCTs (single-patient, double-blind, randomized, multiple crossover design) in 3 patients with stable bronchiectasis.
The primary outcome was patient self-rated symptom scores on visual analogue scales.
Secondary outcome was 24-hour sputum volume.
A clinical efficacy criterion which combined symptoms score and medication preference was also formulated.
Results.
All three patients showed various degrees of improvement on their symptoms and one patient’s (Case 3) 24 h sputum volume decreased from 70 mL to 30 mL.
However, no significant differences were found between individualized herbal decoction and control decoction on symptoms score, or on 24-hour sputum volume.
One patient (Case 2) had clear preference for the individualized herbal decoction over the standard one with the confirmation after unblinding.
We therefore considered this case as clinically important.
Discussion.
N-of-1 trials comply with individualized philosophy of TCM clinical practice and had good compliance.
It is necessary to set up clinical efficacy criteria and to consider the interference of acute exacerbation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Huang, Haiyin& Yang, Peilan& Xue, Jingjing& Tang, Jie& Ding, Liyu& Ma, Ying…[et al.]. 2014. Evaluating the Individualized Treatment of Traditional Chinese Medicine: A Pilot Study of N-of-1 Trials. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1035104
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Huang, Haiyin…[et al.]. Evaluating the Individualized Treatment of Traditional Chinese Medicine: A Pilot Study of N-of-1 Trials. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-1035104
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Huang, Haiyin& Yang, Peilan& Xue, Jingjing& Tang, Jie& Ding, Liyu& Ma, Ying…[et al.]. Evaluating the Individualized Treatment of Traditional Chinese Medicine: A Pilot Study of N-of-1 Trials. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-1035104
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1035104
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر