Antioxidant and Anti-Inflammatory Activities of Phenolic-Enriched Extracts of Smilax glabra
المؤلفون المشاركون
Lu, Chuanjian
Lu, Chuan-li
Zhu, Wei
Wang, Min
Xu, Xiao-jie
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-11-11
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Smilax glabra Roxb.
has been used for a long time as both food and folk medicine.
In the present study, phenolic-enriched extract of S.
glabra (PEESG) was extracted with 70% ethanol and purified by HP-20 column chromatography.
Its antioxidant and anti-inflammatory activities were evaluated by radical scavenging assay, reducing power determination, and lipopolysaccharide (LPS)-induced RAW264.7 cells assays, respectively.
PEESG exhibited obviously scavenging capacity for DPPH and ABTS radicals, as well as significant reducing power for ferric ion.
Particularly, PEESG (12.5–50 μg/mL) showed a significantly higher efficiency for scavenging ABTS than that of ascorbic acid and no significant difference with ascorbic acid for DPPH scavenging.
PEESG also possessed a significant suppression effect on proinflammatory mediators production, such as nitric oxide (NO), tumor necrosis factor- α (TNF- α ), and interleukin-6 (IL-6), in LPS-induced RAW264.7 cells.
In addition, the main ingredients of PEESG were identified using ultrahigh pressure liquid chromatography coupled to electrospray mass spectrometry (U-HPLC-ESI-MS).
Seventeen components, including 5-O-caffeoylshikimic acid, neoastilbin, astilbin, neoisoastilbin, isoastilbin, engetin and isoengeletin were identified.
These findings strongly suggest the potential of PEESG as a natural antioxidant and anti-inflammatory agent.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lu, Chuan-li& Zhu, Wei& Wang, Min& Xu, Xiao-jie& Lu, Chuanjian. 2014. Antioxidant and Anti-Inflammatory Activities of Phenolic-Enriched Extracts of Smilax glabra. Evidence-Based Complementary and Alternative Medicine،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1035448
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lu, Chuan-li…[et al.]. Antioxidant and Anti-Inflammatory Activities of Phenolic-Enriched Extracts of Smilax glabra. Evidence-Based Complementary and Alternative Medicine No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1035448
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lu, Chuan-li& Zhu, Wei& Wang, Min& Xu, Xiao-jie& Lu, Chuanjian. Antioxidant and Anti-Inflammatory Activities of Phenolic-Enriched Extracts of Smilax glabra. Evidence-Based Complementary and Alternative Medicine. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1035448
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1035448
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر