Effects of Short Term Exposure of Atrazine on the Liver and Kidney of Normal and Diabetic Rats
المؤلفون المشاركون
Jestadi, Dinesh Babu
Phaniendra, Alugoju
Babji, Undru
Srinu, Thupakula
Shanmuganathan, Bhavatharini
Periyasamy, Latha
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-09-29
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
The present study evaluates the effects of short term (15 days) exposure of low dose (300 μg kg−1) of atrazine (2-chloro-4-ethylamino-6-isopropylamino-1,3,5-triazine) on antioxidant status and markers of liver and kidney damage in normal (nondiabetic) and diabetic male Wistar rats.
Rats were divided into four groups: Group I as normal control, Group II as atrazine treated, Group III as diabetic control, and Group IV as atrazine treated diabetic rats.
Atrazine administration resulted in increased MDA concentration as well as increased activities of SOD, CAT, and GPx in both liver and kidney of atrazine treated and atrazine treated diabetic rats.
However, GSH level was decreased in both liver and kidney of atrazine treated and atrazine treated diabetic rats.
Atrazine administration led to significant increase in liver damage biomarkers such as AST, ALT, and ALP as well as kidney damage biomarkers such as creatinine and urea in both normal and diabetic rats, but this increase was more pronounced in diabetic rats when compared to normal rats.
In conclusion, the results of the present study demonstrate that short term exposure of atrazine at a dose of 300 μg kg−1 could potentially induce oxidative damage in liver and kidney of both normal and diabetic rats.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jestadi, Dinesh Babu& Phaniendra, Alugoju& Babji, Undru& Srinu, Thupakula& Shanmuganathan, Bhavatharini& Periyasamy, Latha. 2014. Effects of Short Term Exposure of Atrazine on the Liver and Kidney of Normal and Diabetic Rats. Journal of Toxicology،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1043200
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jestadi, Dinesh Babu…[et al.]. Effects of Short Term Exposure of Atrazine on the Liver and Kidney of Normal and Diabetic Rats. Journal of Toxicology No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1043200
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jestadi, Dinesh Babu& Phaniendra, Alugoju& Babji, Undru& Srinu, Thupakula& Shanmuganathan, Bhavatharini& Periyasamy, Latha. Effects of Short Term Exposure of Atrazine on the Liver and Kidney of Normal and Diabetic Rats. Journal of Toxicology. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1043200
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1043200
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر