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New Onset of DermatomyositisPolymyositis during Anti-TNF-α Therapies: A Systematic Literature Review
المؤلفون المشاركون
Brunasso, Alexandra Maria Giovanna
Aberer, Werner
Massone, Cesare
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-01-29
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
We performed a systematic search of databases from 1990 to 2013 to identify articles concerning the new onset of dermatomyositis/polymyositis (DM/PM) in patients treated with anti-TNF-α therapy.
We retrieved 13 publications describing 20 patients where the new onset of DM/PM after anti-TNF-α therapy was recorded.
17 patients were affected by rheumatoid arthritis (RA), one by Crohn’s disease, one by ankylosing spondilytis, and one by seronegative arthritis.
In 91% of the cases antinuclear autoantibodies were detected after the introduction of anti-TNF-α therapy.
In 6 patients antisynthetase antibodies were detected and other clinical findings as interstitial lung disease (ILD) were recorded.
Improvement of DM/PM after anti-TNF suspension (with the concomitant use of other immunosuppressors) was recorded in 94% of cases.
The emergence of DM/PM and antisynthetase syndrome seem to be associated with the use of anti-TNF-α agents, especially in patients with chronic inflammatory diseases (mainly RA) with positive autoantibodies before therapy initiation.
In particular, physicians should pay attention to patients affected by RA with positive antisynthetase antibodies and/or history of ILD.
In those cases, the use of the TNF-α blocking agents may trigger the onset of PM/DM or antisynthetase syndrome or may aggravate/trigger the lung disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Brunasso, Alexandra Maria Giovanna& Aberer, Werner& Massone, Cesare. 2014. New Onset of DermatomyositisPolymyositis during Anti-TNF-α Therapies: A Systematic Literature Review. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1048613
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Brunasso, Alexandra Maria Giovanna…[et al.]. New Onset of DermatomyositisPolymyositis during Anti-TNF-α Therapies: A Systematic Literature Review. The Scientific World Journal No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1048613
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Brunasso, Alexandra Maria Giovanna& Aberer, Werner& Massone, Cesare. New Onset of DermatomyositisPolymyositis during Anti-TNF-α Therapies: A Systematic Literature Review. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1048613
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1048613
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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