Pharmacological Treatment of Idiopathic Pulmonary Fibrosis: Current Approaches, Unsolved Issues, and Future Perspectives
المؤلفون المشاركون
Kreuter, Michael
Spagnolo, Paolo
Bonella, Francesco
Wijsenbeek, Marlies
Maher, Toby M.
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-08
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Idiopathic pulmonary fibrosis (IPF) is a devastating condition with a 5-year survival of approximately 20%.
The disease primarily occurs in elderly patients.
IPF is a highly heterogeneous disorder with a clinical course that varies from prolonged periods of stability to episodes of rapid deterioration.
In the last decade, improved understanding of disease mechanisms along with a more precise disease definition has allowed the design and completion of a number of high-quality clinical trials.
Yet, until recently, IPF was essentially an untreatable disease.
Finally, pirfenidone and nintedanib, two compounds with antifibrotic properties, have consistently proven effective in reducing functional decline and disease progression in IPF.
This is a major breakthrough for patients and physicians alike, but there is still a long way to go.
In fact, neither pirfenidone nor nintedanib is a cure for IPF, and most patients continue to progress despite treatment.
As such, comprehensive care of patients with IPF, including management of comorbidities/complications and physical debility and timely referral for palliative care or, in a small number of highly selected patients, lung transplantation, remains essential.
Several agents with high potential are currently being tested and many more are ready to be evaluated in clinical trials.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kreuter, Michael& Bonella, Francesco& Wijsenbeek, Marlies& Maher, Toby M.& Spagnolo, Paolo. 2015. Pharmacological Treatment of Idiopathic Pulmonary Fibrosis: Current Approaches, Unsolved Issues, and Future Perspectives. BioMed Research International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1055102
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kreuter, Michael…[et al.]. Pharmacological Treatment of Idiopathic Pulmonary Fibrosis: Current Approaches, Unsolved Issues, and Future Perspectives. BioMed Research International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1055102
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kreuter, Michael& Bonella, Francesco& Wijsenbeek, Marlies& Maher, Toby M.& Spagnolo, Paolo. Pharmacological Treatment of Idiopathic Pulmonary Fibrosis: Current Approaches, Unsolved Issues, and Future Perspectives. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1055102
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1055102
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر