Value of 18-F-FDG PETCT and CT in the Diagnosis of Indeterminate Adrenal Masses

الملخص EN

The purpose of this paper was to study the value of 18-FDG PET/CT and reassess the value of CT for the characterization of indeterminate adrenal masses.

66 patients with 67 indeterminate adrenal masses were included in our study.

CT/MRI images and 18F-FDG PET/CT data were evaluated blindly for tumor morphology, enhancement features, apparent diffusion coefficient values, maximum standardized uptake values, and adrenal-to-liver maxSUV ratio.

The study population comprised pathologically confirmed 16 adenomas, 19 metastases, and 32 adrenocortical carcinomas.

Macroscopic fat was observed in 62.5% of the atypical adenomas at CT but not in malignant masses.

On 18F-FDG PET/CT, SUVmax and adrenal-to-liver maxSUV ratio were significantly lower in adenomas than in malignant tumors.

An SUVmax value of less than 3.7 or an adrenal-to-liver maxSUV ratio of less than 1.29 is highly predictive of benignity.