Neutrophil Migration in the Activation of the Innate Immune Response to Different Flavobacterium psychrophilum Vaccines in Zebrafish (Danio rerio)
المؤلفون المشاركون
Solís, Camila J.
Poblete-Morales, Matías
Cabral, Sergio
Valdés, Juan A.
Reyes, Ariel E.
Avendaño-Herrera, Ruben
Feijóo, Carmen G.
المصدر
Journal of Immunology Research
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-02-28
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Flavobacterium psychrophilum is a Gram-negative bacterium, responsible for the bacterial cold-water disease and the rainbow trout fry syndrome in freshwater salmonid fish.
At present, there is only one commercial vaccine in Chile, made with two Chilean F.
psychrophilum isolates and another licensed in Europe.
The present study analyzed neutrophil migration, as a marker of innate immune activation, in zebrafish (Danio rerio) in response to different F.
psychrophilum bath vaccines, which is the first step in evaluating vaccine effectiveness and efficiency in fish.
Results indicated that bacterins of the LM-02-Fp isolate were more immunogenic than those from the LM-13-Fp isolate.
However, no differences were observed between the same bacteria inactivated by either formaldehyde or heat.
Importantly, the same vaccine formulation without an adjuvant only triggered a mild neutrophil migration compared to the complete vaccine.
Observations also found that, after a year of storage at 4°C, the activation of the innate immune system by the different vaccines was considerably decreased.
Finally, new vaccine formulations prepared with heat and formaldehyde inactivated LM-02-Fp were significantly more efficient than the available commercial vaccine in regard to stimulating the innate immune system.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Solís, Camila J.& Poblete-Morales, Matías& Cabral, Sergio& Valdés, Juan A.& Reyes, Ariel E.& Avendaño-Herrera, Ruben…[et al.]. 2015. Neutrophil Migration in the Activation of the Innate Immune Response to Different Flavobacterium psychrophilum Vaccines in Zebrafish (Danio rerio). Journal of Immunology Research،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1068504
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Solís, Camila J.…[et al.]. Neutrophil Migration in the Activation of the Innate Immune Response to Different Flavobacterium psychrophilum Vaccines in Zebrafish (Danio rerio). Journal of Immunology Research No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1068504
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Solís, Camila J.& Poblete-Morales, Matías& Cabral, Sergio& Valdés, Juan A.& Reyes, Ariel E.& Avendaño-Herrera, Ruben…[et al.]. Neutrophil Migration in the Activation of the Innate Immune Response to Different Flavobacterium psychrophilum Vaccines in Zebrafish (Danio rerio). Journal of Immunology Research. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1068504
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1068504
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر