ADAMTS-7 Exhibits Elevated Expression in Cartilage of Osteonecrosis of Femoral Head and Has a Positive Correlation with TNF- α and NF- κB P65

المؤلفون المشاركون

Li, Jing-kun
Cheng, Lei
Zhao, Yun-peng
Guo, Ying-jun
Liu, Yi
Zhang, Wei
Wang, Shuai-shuai
Zhang, Yuan-qiang
Pan, Xin
Nie, Lin

المصدر

Mediators of Inflammation

العدد

المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2015-01-14

دولة النشر

مصر

عدد الصفحات

10

التخصصات الرئيسية

الأمراض

الملخص EN

ADAMTS-7 has been reported to exaggerate cartilage degeneration and to be associated with TNF-α and NF-κB signaling pathway.

In this study we compared the expression of ADAMTS-7, TNF-α, and Phospho-NF-κB in patients with femoral neck fracture (FNF) and osteonecrosis of femoral head (ONFH) at different stages.

We found that expression of ADAMTS-7, TNF-α, and Phospho-NF-κB was significantly upregulated in ONFH patients’ articular cartilage and related to the pathogenesis of ONFH.

Thus we conclude that ADAMTS-7 level appears to be positively associated with expression of TNF-α and Phospho-NF-κB P65 in cartilage, which may imply its association with cartilage destruction of ONFH.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Li, Jing-kun& Cheng, Lei& Zhao, Yun-peng& Guo, Ying-jun& Liu, Yi& Zhang, Wei…[et al.]. 2015. ADAMTS-7 Exhibits Elevated Expression in Cartilage of Osteonecrosis of Femoral Head and Has a Positive Correlation with TNF- α and NF- κB P65. Mediators of Inflammation،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1072178

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Li, Jing-kun…[et al.]. ADAMTS-7 Exhibits Elevated Expression in Cartilage of Osteonecrosis of Femoral Head and Has a Positive Correlation with TNF- α and NF- κB P65. Mediators of Inflammation No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1072178

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Li, Jing-kun& Cheng, Lei& Zhao, Yun-peng& Guo, Ying-jun& Liu, Yi& Zhang, Wei…[et al.]. ADAMTS-7 Exhibits Elevated Expression in Cartilage of Osteonecrosis of Femoral Head and Has a Positive Correlation with TNF- α and NF- κB P65. Mediators of Inflammation. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1072178

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1072178