Circadian System and Melatonin Hormone: Risk Factors for Complications during Pregnancy
المؤلفون المشاركون
Vera, J.
Venegas, C.
Pino, F.
Lagunas, C.
Valenzuela, Francisco J.
المصدر
Obstetrics and Gynecology International
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-02
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Pregnancy is a complex and well-regulated temporal event in which several steps are finely orchestrated including implantation, decidualization, placentation, and partum and any temporary alteration has serious effects on fetal and maternal health.
Interestingly, alterations of circadian rhythms (i.e., shiftwork) have been correlated with increased risk of preterm delivery, intrauterine growth restriction, and preeclampsia.
In the last few years evidence is accumulating that the placenta may have a functional circadian system and express the clock genes Bmal1, Per1-2, and Clock.
On the other hand, there is evidence that the human placenta synthesizes melatonin, hormone involved in the regulation of the circadian system in other tissues.
Moreover, is unknown the role of this local production of melatonin and whether this production have a circadian pattern.
Available information indicates that melatonin induces in placenta the expression of antioxidant enzymes catalase and superoxide dismutase, prevents the injury produced by oxidative stress, and inhibits the expression of vascular endothelial growth factor (VEGF) a gene that in other tissues is controlled by clock genes.
In this review we aim to analyze available information regarding clock genes and clock genes controlled genes such as VEGF and the possible role of melatonin synthesis in the placenta.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Valenzuela, Francisco J.& Vera, J.& Venegas, C.& Pino, F.& Lagunas, C.. 2015. Circadian System and Melatonin Hormone: Risk Factors for Complications during Pregnancy. Obstetrics and Gynecology International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1075515
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Valenzuela, Francisco J.…[et al.]. Circadian System and Melatonin Hormone: Risk Factors for Complications during Pregnancy. Obstetrics and Gynecology International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1075515
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Valenzuela, Francisco J.& Vera, J.& Venegas, C.& Pino, F.& Lagunas, C.. Circadian System and Melatonin Hormone: Risk Factors for Complications during Pregnancy. Obstetrics and Gynecology International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1075515
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1075515
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر