Mortality in Iranian Patients with Parkinson’s Disease: Cumulative Impact of Cardiovascular Comorbidities as One Major Risk Factor
المؤلفون المشاركون
Shafieesabet, Azadeh
Shafieesabet, Mahdiyeh
Shahidi, Gholam Ali
Lökk, Johan
Delbari, Ahmad
Fereshtehnejad, Seyed-Mohammad
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-10-20
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Mortality rate, life expectancy, survival, and the impact of comorbidities on them in people with Parkinson’s disease (PD) need to be assessed in settings with different sociodemographic backgrounds.
We investigated mortality features in Iranian PD patients focusing on the role of cardiovascular multimorbidity on their survival.
Data on mortality and comorbidity profile was gathered in a cohort of 190 individuals with idiopathic PD referred to a Movement Disorders Clinic.
Standardized mortality ratio (SMR) compared to the Tehran general population was 3.44 and the life expectancy at birth was 67.4 (95% CI: 59.1–75.8) yr.
Patients with at least one cardiovascular comorbidity had a shorter survival time after PD onset (14.0 versus 29.2 yr, p = 0.012 ).
The hazard ratio for death increased 2.8 times (95% CI: 1.5–5.2, p = 0.002 ) with one additional cardiovascular comorbidity.
Among all comorbid conditions, stroke showed the strongest independent effect on mortality in PD patients [HR = 13.1 (95% CI: 2.4–71.7), p = 0.003 ].
Conclusively, life expectancy was slightly lower in Iranian PD patients compared to the general population, while the SMR was high.
Cardiometabolic multimorbidity substantially decreased survival in people with PD.
Our study highlights the need for assessment, prevention, and treatment of cardiovascular morbidities in parkinsonian patients, given their effect on survival.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fereshtehnejad, Seyed-Mohammad& Shafieesabet, Azadeh& Shafieesabet, Mahdiyeh& Shahidi, Gholam Ali& Delbari, Ahmad& Lökk, Johan. 2015. Mortality in Iranian Patients with Parkinson’s Disease: Cumulative Impact of Cardiovascular Comorbidities as One Major Risk Factor. Parkinson’s Disease،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1075914
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fereshtehnejad, Seyed-Mohammad…[et al.]. Mortality in Iranian Patients with Parkinson’s Disease: Cumulative Impact of Cardiovascular Comorbidities as One Major Risk Factor. Parkinson’s Disease No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1075914
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fereshtehnejad, Seyed-Mohammad& Shafieesabet, Azadeh& Shafieesabet, Mahdiyeh& Shahidi, Gholam Ali& Delbari, Ahmad& Lökk, Johan. Mortality in Iranian Patients with Parkinson’s Disease: Cumulative Impact of Cardiovascular Comorbidities as One Major Risk Factor. Parkinson’s Disease. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1075914
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1075914
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر