Pregnancy and Accelerated Phase of Myeloid Chronic Leukemia Treated with Imatinib: A Case Report from a Developing Country
المؤلفون المشاركون
Ngolet, L. O.
Elira Dokekias, Alexis
Kocko, Innocent
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-3، 3ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-03-31
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
Background.
Chronic myeloid leukemia is a hematological malignancy caused by expression of BCR-ABL tyrosine kinase oncogene, product of the t(9;22) Philadelphia translocation.
Accelerated phase of this disease marks the onset of advanced rapidly progressive disease unresponsive to many therapies.
Pregnancy limits broad number of therapies on patients because of their potential teratogenic effects.
We report the case of a pregnant 34-year-old patient on accelerated phase successively managed by imatinib.
She achieved a safe pregnancy and delivered at 39 weeks a healthy baby without congenital abnormalities.
Our case is unusual because of the accelerated phase of the disease.
Case Presentation.
A 34-year-old African female with history of chronic phase of myeloid leukemia on imatinib, lost to follow-up for 4 months, presented to the hematological department for abdominal discomfort.
Accelerated phase of chronic myeloid leukemia was diagnosed.
Complete hematological response was achieved on high doses of imatinib.
At the completion of 39 weeks, she delivered a healthy child without congenital anomalies.
Conclusion.
Despite its teratogenic and embryotoxic effects, front line imatinib is the only effective, well-tolerated treatment for patient on accelerated phase that can be offered to patients in sub-Saharan countries.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ngolet, L. O.& Kocko, Innocent& Elira Dokekias, Alexis. 2016. Pregnancy and Accelerated Phase of Myeloid Chronic Leukemia Treated with Imatinib: A Case Report from a Developing Country. Case Reports in Hematology،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1100866
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ngolet, L. O.…[et al.]. Pregnancy and Accelerated Phase of Myeloid Chronic Leukemia Treated with Imatinib: A Case Report from a Developing Country. Case Reports in Hematology No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1100866
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ngolet, L. O.& Kocko, Innocent& Elira Dokekias, Alexis. Pregnancy and Accelerated Phase of Myeloid Chronic Leukemia Treated with Imatinib: A Case Report from a Developing Country. Case Reports in Hematology. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1100866
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1100866
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر