Pigmentation Effect of Rice Bran Extracted Minerals Comprising Soluble Silicic Acids
المؤلفون المشاركون
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-11-01
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Our investigation focused on identifying melanogenesis effect of soluble minerals in rice bran ash extract (RBE) which include orthosilicic acid (OSA).
Melanocytes were apparently normal in terms of morphology.
It was, however, shown that they were stressed a little in the RBE and OSA added media in aspect of LDH activity.
Melanin synthesis and intracellular tyrosinase activity were increased by treatment of RBE which is similar to that of OSA.
The Western blotting results showed that TRP-1, tyrosinase, and MITF expression levels were 2-3 times higher in the OSA and RBE groups compared to the control group which promoted melanin synthesis through CREB phosphorylation.
Moreover, histology and immunohistochemistry were shown to have similar result to that of protein expression.
As a result, minerals which comprise orthosilicic acid has the potential to promote melanogenesis and both RBE and OSA have similar cell viability, protein expression, and immunostaining results, suggesting that RBE comprises specific minerals which promote melanin synthesis through increasing of MITF and CREB phosphorylation.
Therefore, RBE could be used as a novel therapeutic approach to combat melanin deficiency related diseases by stimulating melanocytes via its soluble Si and mineral components.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jang, Hyun-Jun& Seo, Young-Kwon. 2016. Pigmentation Effect of Rice Bran Extracted Minerals Comprising Soluble Silicic Acids. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104045
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jang, Hyun-Jun& Seo, Young-Kwon. Pigmentation Effect of Rice Bran Extracted Minerals Comprising Soluble Silicic Acids. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1104045
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jang, Hyun-Jun& Seo, Young-Kwon. Pigmentation Effect of Rice Bran Extracted Minerals Comprising Soluble Silicic Acids. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104045
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104045
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر