Effect of Betula pendula Leaf Extract on α-Glucosidase and Glutathione Level in Glucose-Induced Oxidative Stress
المؤلفون المشاركون
Bljajić, Kristina
Šoštarić, Nina
Petlevski, Roberta
Vujić, Lovorka
Brajković, Andrea
Fumić, Barbara
de Carvalho, Isabel Saraiva
Končić, Marijana Zovko
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-09-07
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
B.
pendula leaf is a common ingredient in traditional herbal combinations for treatment of diabetes in southeastern Europe.
Present study investigated B.
pendula ethanolic and aqueous extract as inhibitors of carbohydrate hydrolyzing enzymes, as well as their ability to restore glutathione concentration in Hep G2 cells subjected to glucose-induced oxidative stress.
Phytochemical analysis revealed presence of rutin and other quercetin derivatives, as well as chlorogenic acid.
In general, ethanolic extract was richer in phenolic substances than the aqueous extract.
Furthermore, a comprehensive analysis of antioxidant activity of two extracts (determined by DPPH and ABTS radical scavenging activity, total antioxidant activity, and chelating activity as well as ferric-reducing antioxidant power) has shown that ethanolic extract was better radical scavenger and metal ion reductant.
In addition, ethanolic extract effectively increased cellular glutathione levels caused by hyperglycemia and inhibited α-glucosidase with the activity comparable to that of acarbose.
Therefore, in vitro research using B.
pendula plant extracts has confirmed their antidiabetic properties.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bljajić, Kristina& Šoštarić, Nina& Petlevski, Roberta& Vujić, Lovorka& Brajković, Andrea& Fumić, Barbara…[et al.]. 2016. Effect of Betula pendula Leaf Extract on α-Glucosidase and Glutathione Level in Glucose-Induced Oxidative Stress. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104425
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bljajić, Kristina…[et al.]. Effect of Betula pendula Leaf Extract on α-Glucosidase and Glutathione Level in Glucose-Induced Oxidative Stress. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1104425
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bljajić, Kristina& Šoštarić, Nina& Petlevski, Roberta& Vujić, Lovorka& Brajković, Andrea& Fumić, Barbara…[et al.]. Effect of Betula pendula Leaf Extract on α-Glucosidase and Glutathione Level in Glucose-Induced Oxidative Stress. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104425
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1104425
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر