Parkinson’s Disease and Homocysteine: A Community-Based Study in a Folate and Vitamin B12 Deficient Population
المؤلفون المشاركون
Wei, Zhang
Tiandong, Wang
Yang, Li
Huaxing, Meng
Guowen, Min
Yalan, Fang
Xiaoyuan, Niu
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-08-31
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Homocysteine (Hcy) levels were higher in patients with Parkinson’s disease (PD).
This could be partially explained by levodopa treatment.
Whether untreated PD patients have higher Hcy levels is contradictory.
Methods.
A community-based study was conducted using a two-stage approach for subjects ≥ 55 years to find PD patients in 3 towns of Lüliang City.
Blood samples were collected.
Serum Hcy, folate, and vitamin B12 concentrations were measured.
For each untreated PD patient, 5 controls were selected matched with age and sex to evaluate the relationship between Hcy levels and PD.
Results.
Of 6338 eligible residents, 72.7% participated in the study.
31 PD cases were identified.
The crude prevalence of PD for people ≥ 55 years was 0.67%.
Blood samples were collected from 1845 subjects, including 17 untreated PD patients.
There was no difference for concentrations of serum Hcy, folate, and vitamin B12 between cases and controls ( P > 0.05 ).
In univariate and multivariate analysis, there was significant inverse relation between PD and current smoking ( P < 0.05 ).
No other factor was significant statistically.
Conclusions.
The prevalence of PD was comparable to earlier studies in China.
Hyperhomocysteinemia was not a risk factor of PD, as well as folate and vitamin B12 deficiency.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wei, Zhang& Tiandong, Wang& Yang, Li& Huaxing, Meng& Guowen, Min& Yalan, Fang…[et al.]. 2016. Parkinson’s Disease and Homocysteine: A Community-Based Study in a Folate and Vitamin B12 Deficient Population. Parkinson’s Disease،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1115282
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wei, Zhang…[et al.]. Parkinson’s Disease and Homocysteine: A Community-Based Study in a Folate and Vitamin B12 Deficient Population. Parkinson’s Disease No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1115282
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wei, Zhang& Tiandong, Wang& Yang, Li& Huaxing, Meng& Guowen, Min& Yalan, Fang…[et al.]. Parkinson’s Disease and Homocysteine: A Community-Based Study in a Folate and Vitamin B12 Deficient Population. Parkinson’s Disease. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1115282
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1115282
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر