Multiple Functions of MSCA-1TNAP in Adult Mesenchymal ProgenitorStromal Cells

المؤلفون المشاركون

Estève, David
Galitzky, Jean
Bouloumié, Anne
Fonta, Caroline
Buchet, René
Magne, David

المصدر

Stem Cells International

العدد

المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2015-12-29

دولة النشر

مصر

عدد الصفحات

8

الملخص EN

Our knowledge about mesenchymal stem cells has considerably grown in the last years.

Since the proof of concept of the existence of such cells in the 70s by Friedenstein et al., a growing mass of reports were conducted for a better definition of these cells and for the reevaluation from the term “mesenchymal stem cells” to the term “mesenchymal stromal cells (MSCs).” Being more than a semantic shift, concepts behind this new terminology reveal the complexity and the heterogeneity of the cells grouped in MSC family especially as these cells are present in nearly all adult tissues.

Recently, mesenchymal stromal cell antigen-1 (MSCA-1)/tissue nonspecific alkaline phosphatase (TNAP) was described as a new cell surface marker of MSCs from different tissues.

The alkaline phosphatase activity of this protein could be involved in wide range of MSC features described below from cell differentiation to immunomodulatory properties, as well as occurrence of pathologies.

The present review aims to decipher and summarize the role of TNAP in progenitor cells from different tissues focusing preferentially on brain, bone marrow, and adipose tissue.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Estève, David& Galitzky, Jean& Bouloumié, Anne& Fonta, Caroline& Buchet, René& Magne, David. 2015. Multiple Functions of MSCA-1TNAP in Adult Mesenchymal ProgenitorStromal Cells. Stem Cells International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1116143

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Estève, David…[et al.]. Multiple Functions of MSCA-1TNAP in Adult Mesenchymal ProgenitorStromal Cells. Stem Cells International Vol. 2016, no. 2016 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1116143

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Estève, David& Galitzky, Jean& Bouloumié, Anne& Fonta, Caroline& Buchet, René& Magne, David. Multiple Functions of MSCA-1TNAP in Adult Mesenchymal ProgenitorStromal Cells. Stem Cells International. 2015. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1116143

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1116143