A Prospective and Controlled Clinical Trial on Stromal Vascular Fraction Enriched Fat Grafts in Secondary Breast Reconstruction
المؤلفون المشاركون
Tissiani, L. A. L.
Alonso, Nivaldo
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-28
دولة النشر
مصر
عدد الصفحات
12
الملخص EN
Background.
Fat grafting is a tremendous tool in secondary breast reconstruction.
Stromal vascular fraction (SVF) enriched fat grafts have been presenting promising results regarding volume maintenance.
Methods.
We developed a method that produces a superior SVF enrichment rate (2 : 1) in the operating theatre.
This prospective and controlled trial analyzed quantitatively and qualitatively fat grafts with (stem cells group, SG) and without (control group, CG) SVF enrichment in secondary breast reconstruction, through MRI-based volumetry, immunophenotyping, and cell counting.
Also, patient satisfaction, aesthetic outcomes, and complications were analyzed.
Results.
Volumetric persistence in the SG was 78,9% and 51,4% in the CG; however it did not reach statistical significant difference.
CD90 was the only marker highly expressed in the SG and showed a positive correlation with volumetric persistence (r=0.651, p=0.03).
Fat necrosis occurred in 4 patients in the SG and in none in the CG.
Patients in the CG showed a trend to be more satisfied.
Considering aesthetics, both groups presented improvements.
No locoregional recurrences were observed.
Conclusions.
Results are encouraging despite the fact that SVF enrichment in a higher supplementation rate did not improve, with statistical significance, fat graft volumetric persistence.
Enriched fat grafts have proven to be safe in a 3-year follow-up.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tissiani, L. A. L.& Alonso, Nivaldo. 2015. A Prospective and Controlled Clinical Trial on Stromal Vascular Fraction Enriched Fat Grafts in Secondary Breast Reconstruction. Stem Cells International،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1116270
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tissiani, L. A. L.& Alonso, Nivaldo. A Prospective and Controlled Clinical Trial on Stromal Vascular Fraction Enriched Fat Grafts in Secondary Breast Reconstruction. Stem Cells International Vol. 2016, no. 2016 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1116270
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tissiani, L. A. L.& Alonso, Nivaldo. A Prospective and Controlled Clinical Trial on Stromal Vascular Fraction Enriched Fat Grafts in Secondary Breast Reconstruction. Stem Cells International. 2015. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1116270
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1116270
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر