Insulin-Like Growth Factor-1 and Selected Insulin-Like Growth Factor Binding Protein Concentrations during an Ultramarathon Sled Dog Race
المؤلفون المشاركون
Brunke, Matthew W.
Frye, Christopher W.
Levine, Corri B.
Hansen, Cristina
Wakshlag, Joseph J.
المصدر
العدد
المجلد 2016، العدد 2016 (31 ديسمبر/كانون الأول 2016)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2016-09-05
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
The objective of this study was to investigate the effects of running a 1000-mile (1600 km) endurance sled dog race on serum insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding proteins 1 and 3 (IGFBP-1 and IGFBP-3).
Serum was examined from 12 sled dogs prior to the race, at midrace (approximately 690 km), and again at the finish.
IGF-1, IGFBP-1, and IGFBP-3 were assessed using radioimmunoassay or enzyme linked immune-absorbance assays.
Mean prerace concentrations were significantly higher than midrace and end-race concentrations at 215.93 ± 80.51 ng/mL, 54.29 ± 25.45 ng/mL, and 55.53 ± 28.25 ng/mL, respectively ( P < 0.001 ).
Mean IGFBP-1 concentrations were not different across these time periods at 24.1 ± 15.8 ng/mL, 25.7 ± 14.0 ng/mL, and 26.6 ± 17.6 ng/mL, respectively.
IGFBP-3 concentrations showed a modest significant decrease across time periods at 3,067 ± 2,792 ng/mL, 2,626 ± 2,310 ng/mL, and 2,331 ± 2,301 ng/mL, respectively ( P < 0.01 ).
Endurance sled dogs show a precipitous drop in serum IGF-1 concentrations.
These differences may be related to fuel utilization and excessive negative energy balance associated with the loss of body condition during racing.
The relative stability of IGFBP-1 and IGFBP-3 suggests that IGF-1 anabolic signaling is diminished during ultramarathon racing.
Further studies comparing the influence of time and duration of exercise versus negative energy balance on serum IGF-1 status are warranted to better understand exercise versus negative energy balance differences.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Brunke, Matthew W.& Frye, Christopher W.& Levine, Corri B.& Hansen, Cristina& Wakshlag, Joseph J.. 2016. Insulin-Like Growth Factor-1 and Selected Insulin-Like Growth Factor Binding Protein Concentrations during an Ultramarathon Sled Dog Race. The Scientific World Journal،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1120482
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Brunke, Matthew W.…[et al.]. Insulin-Like Growth Factor-1 and Selected Insulin-Like Growth Factor Binding Protein Concentrations during an Ultramarathon Sled Dog Race. The Scientific World Journal No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1120482
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Brunke, Matthew W.& Frye, Christopher W.& Levine, Corri B.& Hansen, Cristina& Wakshlag, Joseph J.. Insulin-Like Growth Factor-1 and Selected Insulin-Like Growth Factor Binding Protein Concentrations during an Ultramarathon Sled Dog Race. The Scientific World Journal. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1120482
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1120482
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر