Low Hematocrit Is a Strong Predictor of Poor Prognosis in Lung Cancer Patients
المؤلفون المشاركون
Zhang, Xin
Zhang, Fengmin
Qiao, Wenbo
Zhang, Xiansheng
Zhao, Zhefeng
Li, Mingqi
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-10-17
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Morbidity and mortality of lung cancer rank first in China and worldwide.
Thus, noninvasive prognostic biomarkers are critical for clinicians to perform risk assessment in lung cancer patients prior to or during the course of treatment.
In this study, we evaluated the prognostic value of preoperative hematocrit (HCT) count reduction on the long-term survival of lung cancer patients undergoing pneumonectomy and analyzed the correlation between reduced HCT counts and patients’ clinicopathological features.
A total of 1022 patients who underwent surgical treatment in Harbin Medical University Cancer Hospital, China, from February 2006 to December 2013, were enrolled in this study.
The association between the clinicopathologic variables and HCT were evaluated by Mann-Whitney U-test and chi-square test, respectively.
Survival curves were generated using Kaplan-Meier estimates, and differences between the curves were analyzed by a log-rank test.
Multivariable analysis showed that high HCT (P < 0.001, HR: 0.595, 95% CI: 0.458–0.774) was favorable for patients’ survival.
Low HCT patients presented shorter mean months of OS than that of high HCT patients (P < 0.001).
Male adenocarcinoma carcinoma patients with lower body mass index (BMI) and advanced tumor stage were more likely to observe low HCT.
We identified for the first time reduced preoperative HCT count as an independent risk factor leading to poor prognosis in lung cancer patients who underwent surgical treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Xin& Zhang, Fengmin& Qiao, Wenbo& Zhang, Xiansheng& Zhao, Zhefeng& Li, Mingqi. 2018. Low Hematocrit Is a Strong Predictor of Poor Prognosis in Lung Cancer Patients. BioMed Research International،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1128097
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Xin…[et al.]. Low Hematocrit Is a Strong Predictor of Poor Prognosis in Lung Cancer Patients. BioMed Research International No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1128097
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Xin& Zhang, Fengmin& Qiao, Wenbo& Zhang, Xiansheng& Zhao, Zhefeng& Li, Mingqi. Low Hematocrit Is a Strong Predictor of Poor Prognosis in Lung Cancer Patients. BioMed Research International. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1128097
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1128097
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر