Clinical and Pathological Characteristics of Autoimmune Hepatitis with Acute Presentation
المؤلفون المشاركون
Yang, Li
Men, Ruoting
Shen, Yi
Lu, Changli
Liu, Jianping
Ye, Tinghong
المصدر
Canadian Journal of Gastroenterology and Hepatology
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-03-18
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Aim.
To study the differences between acute presentation-autoimmune hepatitis (A-AIH) and chronic autoimmune hepatitis (C-AIH).
Methods.
Through long-term follow-up, 80 patients were included in our study by using the revised international autoimmune hepatitis group (IAIHG) score and were divided into acute and chronic groups for comparison.
Results.
No significant difference was found in the gender, age, IAIHG score (pretreatment/posttreatment), definite diagnosis rate, extrahepatic autoimmune disease, onset time, or treatment before biopsy between the acute and chronic groups.
In terms of clinical symptoms, A-AIH patients were more prone to jaundice, anorexia, yellow urine, and detesting oil than C-AIH patients, but melena only occurred in chronic group (P<0.05).
The acute group exhibited more severe injury upon histological evaluation, with lobular inflammation and bile duct injury, especially central necrosis of the lobule, more pronounced in this group (P<0.05).
Conclusion.
A-AIH had manifestations of acute hepatitis and presented cholestasis.
Serum indicators could preliminarily distinguish A-AIH and C-AIH.
Histologically, the primary manifestation of A-AIH was lobular inflammation, which was usually accompanied by lobular central necrosis.
For the diagnosis of A-AIH, more attention should be paid to long-term follow-up.
This study was registered at ClinicalTrials.gov (identifier: NCT02994537).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shen, Yi& Lu, Changli& Men, Ruoting& Liu, Jianping& Ye, Tinghong& Yang, Li. 2018. Clinical and Pathological Characteristics of Autoimmune Hepatitis with Acute Presentation. Canadian Journal of Gastroenterology and Hepatology،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1130898
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shen, Yi…[et al.]. Clinical and Pathological Characteristics of Autoimmune Hepatitis with Acute Presentation. Canadian Journal of Gastroenterology and Hepatology No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1130898
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shen, Yi& Lu, Changli& Men, Ruoting& Liu, Jianping& Ye, Tinghong& Yang, Li. Clinical and Pathological Characteristics of Autoimmune Hepatitis with Acute Presentation. Canadian Journal of Gastroenterology and Hepatology. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1130898
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1130898
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر