Preventive Effect of Cashew-Derived Protein Hydrolysate with High Fiber on Cerebral Ischemia
المؤلفون المشاركون
Wattanathorn, Jintanaporn
Tiamkao, Somsak
Tong-Un, Terdthai
Wannanon, Panakaporn
Muchimapura, Supaporn
Thukham-mee, Wipawee
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-12-31
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
This study aimed to determine the protective effect of cashew nut-derived protein hydrolysate with high dietary fiber (AO) in cerebral ischemic rats induced by the occlusion of right middle cerebral artery (Rt.MCAO).
Acute toxicity was determined and data showed that LD50 of AO > 5000 mg/kg BW.
To determine the cerebroprotective effect of AO, male Wistar rats were orally given AO at doses of 2, 10, and 50 mg/kg for 14 days and subjected to Rt.MCAO.
Brain infarction volume, neurological score, spatial memory, serum lipid profiles, and C-reactive protein together with the brain oxidative stress status were assessed.
All doses of AO significantly decreased brain infarction in cortex, hippocampus, and striatum together with the decreased oxidative stress status.
The improvement of spatial memory and serum C-reactive protein were also observed in MCAO rats which received AO at all doses.
In addition, the decreased serum cholesterol, TG, and LDL but increased HDL were observed in MCAO rats which received high dose of AO.
Taken all together, AO is the potential protectant against cerebral ischemia.
The improvement of oxidative stress, inflammation, and dyslipidemia might play roles in the actions.
However, further researches are required to understand the precise underlying mechanism.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wattanathorn, Jintanaporn& Thukham-mee, Wipawee& Muchimapura, Supaporn& Wannanon, Panakaporn& Tong-Un, Terdthai& Tiamkao, Somsak. 2017. Preventive Effect of Cashew-Derived Protein Hydrolysate with High Fiber on Cerebral Ischemia. BioMed Research International،Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1137964
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wattanathorn, Jintanaporn…[et al.]. Preventive Effect of Cashew-Derived Protein Hydrolysate with High Fiber on Cerebral Ischemia. BioMed Research International No. 2017 (2017), pp.1-14.
https://search.emarefa.net/detail/BIM-1137964
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wattanathorn, Jintanaporn& Thukham-mee, Wipawee& Muchimapura, Supaporn& Wannanon, Panakaporn& Tong-Un, Terdthai& Tiamkao, Somsak. Preventive Effect of Cashew-Derived Protein Hydrolysate with High Fiber on Cerebral Ischemia. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-14.
https://search.emarefa.net/detail/BIM-1137964
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1137964
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر