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A Case of Cushing’s Syndrome due to Ectopic Adrenocorticotropic Hormone Secretion from Esthesioneuroblastoma with Long Term Follow-Up after Resection
المؤلفون المشاركون
Matheny, Leslee N.
Sarkar, Sudipa
Shi, Hanyuan
Hu, Jiun-Ruey
Harmsen, Hannah
Abel, Ty W.
Jagasia, Shubhada M.
Bao, Shichun
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-02-04
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
We present a case of a 52-year-old male who developed Cushing’s Syndrome due to ectopic adrenocorticotrophic hormone (ACTH) secretion from a large esthesioneuroblastoma (ENB) of the nasal sinuses.
The patient initially presented with polyuria, polydipsia, weakness, and confusion.
Computed tomography scan of the head and magnetic resonance imaging showed a 7 cm skull base mass centered in the right cribriform plate without sella involvement.
Work-up revealed ACTH-dependent hypercortisolemia, which did not suppress appropriately after high-dose dexamethasone.
Subsequent imaging of the chest, abdomen, and pelvis did not reveal other possible ectopic sources of ACTH secretion besides the ENB.
His hospital course was complicated by severe hypokalemia and hyperglycemia before successful surgical resection of the tumor, the biopsy of which showed ENB.
Postoperatively, his ACTH level dropped below the limit of detection.
In the ensuing 4 months, he underwent adjuvant chemoradiation with carboplatin and docetaxel with good response and resolution of hypokalemia and hyperglycemia, with no sign of recurrence as of 30 months postoperatively.
His endogenous cortisol production is rising but has not completely recovered.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Matheny, Leslee N.& Sarkar, Sudipa& Shi, Hanyuan& Hu, Jiun-Ruey& Harmsen, Hannah& Abel, Ty W.…[et al.]. 2018. A Case of Cushing’s Syndrome due to Ectopic Adrenocorticotropic Hormone Secretion from Esthesioneuroblastoma with Long Term Follow-Up after Resection. Case Reports in Endocrinology،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1143004
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Matheny, Leslee N.…[et al.]. A Case of Cushing’s Syndrome due to Ectopic Adrenocorticotropic Hormone Secretion from Esthesioneuroblastoma with Long Term Follow-Up after Resection. Case Reports in Endocrinology No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1143004
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Matheny, Leslee N.& Sarkar, Sudipa& Shi, Hanyuan& Hu, Jiun-Ruey& Harmsen, Hannah& Abel, Ty W.…[et al.]. A Case of Cushing’s Syndrome due to Ectopic Adrenocorticotropic Hormone Secretion from Esthesioneuroblastoma with Long Term Follow-Up after Resection. Case Reports in Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1143004
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1143004
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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