Megestrol Acetate-Induced Symptomatic Hypogonadism in a Male Patient
المؤلفون المشاركون
Munshi, Lubna Bashir
Tsushima, Yumiko
Cheng, Kwan
Brito, Maria
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-3، 3ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-07-18
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
The hypothalamic-pituitary-adrenal (HPA) axis and the hypothalamic-pituitary-gonadal (HPG) axis are very sensitive and can be affected by external factors like stress, starvation, and medication.
Medication-induced suppression of these axes can cause adrenal insufficiency (AI) and hypogonadism.
Exogenous glucocorticoid use is the most common cause of iatrogenic AI.
Our aim is to bring attention to another broadly prescribed medication, megestrol acetate (MA), as the cause of suppression of both these axes.
We report a case of symptomatic hypogonadism and asymptomatic AI in a male patient secondary to MA.
The patient presented with decrease in testicular size and erectile dysfunction.
His total testosterone and morning cortisol levels were low, but FH, LH, and TSH were normal.
His pituitary MRI was unremarkable.
Upon discontinuation of MA, the patient’s testosterone and cortisol levels normalized and his symptoms resolved.
Hypogonadism and AI are known adverse effects of MA, but symptomatic hypogonadism as the primary manifestation has only been reported once in previous literature.
Prolonged hypogonadism can lead to sarcopenia, depression, and osteoporosis, while asymptomatic AI carries the risk of becoming overt AI.
Thus, heightened awareness of the impact of MA on both these axes is necessary.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Munshi, Lubna Bashir& Tsushima, Yumiko& Cheng, Kwan& Brito, Maria. 2018. Megestrol Acetate-Induced Symptomatic Hypogonadism in a Male Patient. Case Reports in Endocrinology،Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1143012
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Munshi, Lubna Bashir…[et al.]. Megestrol Acetate-Induced Symptomatic Hypogonadism in a Male Patient. Case Reports in Endocrinology No. 2018 (2018), pp.1-3.
https://search.emarefa.net/detail/BIM-1143012
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Munshi, Lubna Bashir& Tsushima, Yumiko& Cheng, Kwan& Brito, Maria. Megestrol Acetate-Induced Symptomatic Hypogonadism in a Male Patient. Case Reports in Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1143012
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1143012
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر