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Coexistence of Primary Hyperaldosteronism and Graves’ Disease, a Rare Combination of Endocrine Disorders: Is It beyond a Coincidence—A Case Report and Review of the Literature
المؤلفون المشاركون
Gunathilake, Sonali
Bulugahapitiya, U.
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-10-30
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Primary hyperaldosteronism is a known cause for secondary hypertension.
In addition to its effect on blood pressure, aldosterone exhibits proinflammatory actions and plays a role in immunomodulation/development of autoimmunity.
Recent researches also suggest significant thyroid dysfunction among patients with hyperaldosteronism, but exact causal relationship is not established.
Autoimmune hyperthyroidism (Graves’ disease) and primary hyperaldosteronism rarely coexist but underlying mechanisms associating the two are still unclear.
Case Presentation.
A 32-year-old Sri Lankan female was evaluated for new onset hypertension in association with hypokalemia.
She also had features of hyperthyroidism together with high TSH receptor antibodies suggestive of Graves’ disease.
On evaluation of persistent hypokalemia and hypertension, primary hyperaldosteronism due to right-sided adrenal adenoma was diagnosed.
She was rendered euthyroid with antithyroid drugs followed by right-sided adrenalectomy.
Antithyroid drugs were continued up to 12 months, after which the patient entered remission of Graves’ disease.
Conclusion.
Autoimmune hyperthyroidism and primary hyperaldosteronism rarely coexist and this case report adds to the limited number of cases documented in the literature.
Underlying mechanism associating the two is still unclear but possibilities of autoimmune mechanisms and autoantibodies warrant further evaluation and research.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gunathilake, Sonali& Bulugahapitiya, U.. 2017. Coexistence of Primary Hyperaldosteronism and Graves’ Disease, a Rare Combination of Endocrine Disorders: Is It beyond a Coincidence—A Case Report and Review of the Literature. Case Reports in Endocrinology،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1145092
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gunathilake, Sonali& Bulugahapitiya, U.. Coexistence of Primary Hyperaldosteronism and Graves’ Disease, a Rare Combination of Endocrine Disorders: Is It beyond a Coincidence—A Case Report and Review of the Literature. Case Reports in Endocrinology No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1145092
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gunathilake, Sonali& Bulugahapitiya, U.. Coexistence of Primary Hyperaldosteronism and Graves’ Disease, a Rare Combination of Endocrine Disorders: Is It beyond a Coincidence—A Case Report and Review of the Literature. Case Reports in Endocrinology. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1145092
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1145092
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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