Atypical Complications of Graves’ Disease: A Case Report and Literature Review
المؤلفون المشاركون
Jayyousi, Amin
Siddique, Mashhood Ahmed
Arroub, Shaimaa Ahmed
Ebrahim, Ahmed Hamdi
Baagar, Khaled
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-02-28
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Graves’ disease (GD) may display uncommon manifestations.
We report a patient with rare complications of GD and present a comprehensive literature review.
A 35-year-old woman presented with a two-week history of dyspnea, palpitations, and edema.
She had a raised jugular venous pressure, goiter, and exophthalmos.
Laboratory tests showed pancytopenia, a raised alkaline phosphatase level, hyperbilirubinemia (mainly direct bilirubin), and hyperthyroidism [TSH: <0.01 mIU/L (reference values: 0.45–4.5), fT4: 54.69 pmol/L (reference values: 9.0–20.0), and fT3: >46.08 pmol/L (reference values: 2.6–5.7)].
Her thyroid uptake scan indicated GD.
Echocardiography showed a high right ventricular systolic pressure: 60.16 mmHg.
Lugol’s iodine, propranolol, cholestyramine, and dexamethasone were initiated.
Hematologic investigations uncovered no reason for the pancytopenia; therefore, carbimazole was started.
Workup for hepatic impairment and pulmonary hypertension (PH) was negative.
The patient became euthyroid after 3 months.
Leukocyte and platelet counts and bilirubin levels normalized, and her hemoglobin and alkaline phosphatase levels and right ventricular systolic pressure (52.64 mmHg) improved.
This is the first reported single case of GD with the following three rare manifestations: pancytopenia, cholestatic liver injury, and PH with right-sided heart failure.
With antithyroid drugs treatment, pancytopenia should resolve with euthyroidism, but PH and liver injury may take several months to resolve.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Baagar, Khaled& Siddique, Mashhood Ahmed& Arroub, Shaimaa Ahmed& Ebrahim, Ahmed Hamdi& Jayyousi, Amin. 2017. Atypical Complications of Graves’ Disease: A Case Report and Literature Review. Case Reports in Endocrinology،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1145125
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Baagar, Khaled…[et al.]. Atypical Complications of Graves’ Disease: A Case Report and Literature Review. Case Reports in Endocrinology No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1145125
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Baagar, Khaled& Siddique, Mashhood Ahmed& Arroub, Shaimaa Ahmed& Ebrahim, Ahmed Hamdi& Jayyousi, Amin. Atypical Complications of Graves’ Disease: A Case Report and Literature Review. Case Reports in Endocrinology. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1145125
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1145125
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر