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Waldenstrom’s Macroglobulinemia: A Report of Two Cases, One with Severe Retinopathy and One with Renal Failure
المؤلفون المشاركون
Kudo, Naoko
Usui, Masakatsu
Nishimura, Keisuke
Nakabo, Yukiharu
Yoshida, Ken-ichi
Miki, Kenji
Osafune, Takashi
Imashuku, Shinsaku
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-10-31
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
We report here two cases of Waldenstrom’s macroglobulinemia (WM), one with central nervous system (CNS) symptoms and severe retinopathy and one with renal failure.
In both cases, the serum IgM levels exceeded 3,000 mg/dL and monoclonal IgM-kappa was observed in the blood.
At onset, Case 1, a 63-year-old female, developed CNS symptoms—namely, drowsiness and syncope.
Case 2, a 58-year-old male, had nausea and dysgeusia on admission associated with renal failure, which is quite rare in patients with WM.
Both patients exhibited hyperviscosity-related retinopathy, but it was particularly severe in Case 1: she suddenly lost her vision after admission.
However, her vision recovered completely during treatment.
Case 2 required hemodialysis immediately after admission.
Needle biopsy of his kidney revealed tubulointerstitial nephritis with marked infiltration with CD20-positive lymphoplasmacytic lymphoma cells.
After treatment, Case 1 has been in a remission longer than 8 years, but Case 2 died of pneumonia in 6 months.
Since the initial symptoms of WM are ambiguous and vary significantly and hyperviscosity-related ophthalmological problems or severe renal dysfunction can arise, it is essential to promptly measure serum IgM levels and to institute appropriate care immediately when WM is confirmed in a patient.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kudo, Naoko& Usui, Masakatsu& Nakabo, Yukiharu& Yoshida, Ken-ichi& Miki, Kenji& Osafune, Takashi…[et al.]. 2017. Waldenstrom’s Macroglobulinemia: A Report of Two Cases, One with Severe Retinopathy and One with Renal Failure. Case Reports in Hematology،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1145841
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kudo, Naoko…[et al.]. Waldenstrom’s Macroglobulinemia: A Report of Two Cases, One with Severe Retinopathy and One with Renal Failure. Case Reports in Hematology No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1145841
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kudo, Naoko& Usui, Masakatsu& Nakabo, Yukiharu& Yoshida, Ken-ichi& Miki, Kenji& Osafune, Takashi…[et al.]. Waldenstrom’s Macroglobulinemia: A Report of Two Cases, One with Severe Retinopathy and One with Renal Failure. Case Reports in Hematology. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1145841
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1145841
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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