An Aggressive Form of Langerhan Cell Histiocytosis in an Adult: Therapeutic Challenges
المؤلفون المشاركون
Seegobin, Karan
Maharaj, Satish
Baldeo, Cherisse
Shukri, Amal
Rana, Fauzia
المصدر
Case Reports in Oncological Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-3، 3ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-12-03
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
Langerhans cell histiocytosis (LCH) is rare in adults.
Regular follow-up is mandatory due to reoccurrence.
A 35-year-old male with an incidental left iliac bone lesion was diagnosed with LCH.
He later became symptomatic with hip pain and spread of the disease.
Despite excision of the symptomatic iliac lesion, he had progression while on cytarabine and nivolumab, evidenced by increased bone pain and involvement of other bones on imaging.
He underwent excision of the jaw lesion followed by vinblastine; he was pain free and had stable disease on PET imaging after 3 months.
LCH is an uncommon neoplasia.
Treatment is reserved for symptomatic patients while asymptomatic patients are observed.
Follow-up is imperative due to the risk of reoccurrence.
Despite surgical treatment together with one of the front-line agents for refractory disease, in this case cytarabine, he still had progression of the disease.
Furthermore, the trial of nivolumab was of no benefit.
This case highlights good response to vinblastine which is previously reported to have good success.
No trials are published, and the optimal strategy has yet to be defined.
LCH with multiple bony involvement can be aggressive and therapeutically challenging.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Seegobin, Karan& Maharaj, Satish& Baldeo, Cherisse& Shukri, Amal& Rana, Fauzia. 2017. An Aggressive Form of Langerhan Cell Histiocytosis in an Adult: Therapeutic Challenges. Case Reports in Oncological Medicine،Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1147891
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Seegobin, Karan…[et al.]. An Aggressive Form of Langerhan Cell Histiocytosis in an Adult: Therapeutic Challenges. Case Reports in Oncological Medicine No. 2017 (2017), pp.1-3.
https://search.emarefa.net/detail/BIM-1147891
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Seegobin, Karan& Maharaj, Satish& Baldeo, Cherisse& Shukri, Amal& Rana, Fauzia. An Aggressive Form of Langerhan Cell Histiocytosis in an Adult: Therapeutic Challenges. Case Reports in Oncological Medicine. 2017. Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1147891
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1147891
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر