A Matrix Metalloproteinase-1 Polymorphism, MMP1–1607 (1G>2G), Is Associated with Increased Cancer Risk: A Meta-Analysis Including 21,327 Patients
المؤلفون المشاركون
Wang, Fang-Ming
Zhou, Zhonghan
Zhang, Guiming
Sun, Lijiang
Ma, Xiaocheng
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-12-02
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Although the matrix metalloproteinase-1 (MMP1) polymorphism MMP1–1607 (1G>2G) has been associated with susceptibility to various cancers, these findings are controversial.
Therefore, we conducted this meta-analysis to explore the association between MMP1–1607 (1G>2G) and cancer risk.
A systematic search of literature through PubMed, Embase, ISI Web of Knowledge, and Google Scholar yielded 77 articles with 21,327 cancer patients and 23,245 controls.
The association between the MMP1–1607 (1G>2G) polymorphism and cancer risks was detected in an allele model (2G vs.
1G, overall risk [OR]: 1.174, 95% confidence interval [CI]: 1.107–1.244), a dominant model (2G2G/1G2G vs.
1G1G OR, OR: 1.192, 95% CI: 1.090–1.303), and a recessive model (2G2G vs.
1G2G/1G1G, OR: 1.231, 95% CI: 1.141–1.329).
In subgroup analysis, these associations were detected in both Asians and Caucasians.
After stratification by cancer types, associations were found in lung, colorectal, nervous system, renal, bladder, and nasopharyngeal cancers.
This meta-analysis revealed that MMP1–1607 (1G>2G) polymorphism was significantly associated with elevated risk of cancers.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhou, Zhonghan& Ma, Xiaocheng& Wang, Fang-Ming& Sun, Lijiang& Zhang, Guiming. 2018. A Matrix Metalloproteinase-1 Polymorphism, MMP1–1607 (1G>2G), Is Associated with Increased Cancer Risk: A Meta-Analysis Including 21,327 Patients. Disease Markers،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1153655
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhou, Zhonghan…[et al.]. A Matrix Metalloproteinase-1 Polymorphism, MMP1–1607 (1G>2G), Is Associated with Increased Cancer Risk: A Meta-Analysis Including 21,327 Patients. Disease Markers No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1153655
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhou, Zhonghan& Ma, Xiaocheng& Wang, Fang-Ming& Sun, Lijiang& Zhang, Guiming. A Matrix Metalloproteinase-1 Polymorphism, MMP1–1607 (1G>2G), Is Associated with Increased Cancer Risk: A Meta-Analysis Including 21,327 Patients. Disease Markers. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1153655
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1153655
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر