Efficacy of Traditional Chinese Medicine Tonifying Kidney (Bushen) and Activating Blood (Huoxue) Prescription for Premature Ovarian Insufficiency: A Systematic Review and Meta-Analysis
المؤلفون المشاركون
Li, Hui-fang
Shen, Qi-hong
Feng, Zhang-feng
Chen, Wei-min
Yu, Li-ying
Chen, Wen-Jun
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-04-21
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Context.
Premature ovarian insufficiency (POI) is one of the difficult gynecological diseases with complex etiologies.
Tonifying kidney (bushen) and activating blood (huoxue) prescription (TKABP) is a popular traditional Chinese medicine (TCM) therapy which is commonly applied for POI.
However, its efficacy and safety are still controversial.
Objective.
We carried out this systematic review and meta-analysis to evaluate the effectiveness of TKABP on POI.
Methods.
The following eight databases were searched from the establishment to September 30, 2019, for randomized controlled trials (RCTs): PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), the Chinese BioMedical database (CBM), Chinese Scientific Journal Database (VIP), and the Wanfang database.
The quality of evidence was estimated by the Grading of Recommendations Assessment, Development, and Evaluation (GRADE).
Results.
Twenty-three RCTs involving 1712 patients with POI were included.
Compared to hormone therapy (HT) groups, TKABP groups showed a significantly higher total effective rate (RR: 1.10; 95% CI: 1.04–1.17; P<0.01, I2 = 32%).
In addition, TKABP groups revealed a better improvement in terms of serum follicle-stimulating hormone (FSH) levels, serum estradiol (E2) levels, peak systolic velocity (PSV) of ovarian stromal blood, and Kupperman index (KI) score.
However, serum luteinizing hormone (LH) levels and ovarian volume (OV) showed no significant statistical difference.
Subgroup analyses showed that herbal paste and 3 months of treatment duration had a greater effect on the improvement of hormone levels.
Besides, the occurrence of related adverse events in TKABP groups was lower than that in HT groups.
Conclusions.
Our review suggests that TKABP appears to be an effective and safe measure for patients with POI, and the herbal paste may be superior.
However, the methodological quality of included RCTs was unsatisfactory, and it is necessary to verify its effectiveness with furthermore standardized researches of rigorous design.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Hui-fang& Shen, Qi-hong& Chen, Wen-Jun& Chen, Wei-min& Feng, Zhang-feng& Yu, Li-ying. 2020. Efficacy of Traditional Chinese Medicine Tonifying Kidney (Bushen) and Activating Blood (Huoxue) Prescription for Premature Ovarian Insufficiency: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1154955
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Hui-fang…[et al.]. Efficacy of Traditional Chinese Medicine Tonifying Kidney (Bushen) and Activating Blood (Huoxue) Prescription for Premature Ovarian Insufficiency: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-13.
https://search.emarefa.net/detail/BIM-1154955
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Hui-fang& Shen, Qi-hong& Chen, Wen-Jun& Chen, Wei-min& Feng, Zhang-feng& Yu, Li-ying. Efficacy of Traditional Chinese Medicine Tonifying Kidney (Bushen) and Activating Blood (Huoxue) Prescription for Premature Ovarian Insufficiency: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1154955
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154955
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر