Gypsum-Based Material for Dental Pulp Capping: Effect of Chitosan and BMP-2 on Physical, Mechanical, and Cellular Properties

المؤلفون المشاركون

Husein, Adam
Subhi, Hasan
Reza, Fazal
Al Shehadat, Saaid Ayesh
Nurul, Asma-Abdullah

المصدر

International Journal of Biomaterials

العدد

المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-7، 7ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2018-07-26

دولة النشر

مصر

عدد الصفحات

7

التخصصات الرئيسية

الطب البشري

الملخص EN

Effective pulp capping material must be biocompatible and have the ability to induce dentin bridge formation as well as having suitable physical and mechanical properties; however, many current materials do not satisfy the clinical requirements.

This study aimed to assess the physical and mechanical properties of gypsum-based chitosan material (Gp-CT) and to evaluate its effects on cellular properties of stem cells from human exfoliated deciduous teeth (SHED).

The experimental material was prepared with different concentrations of chitosan (CT) with or without BMP-2.

Then, setting time, compressive strength, and pH were determined.

In addition, cell viability, alkaline phosphatase (ALP) activity, and cell attachment were assessed.

The setting time, compressive strength, and pH obtained were 4.1–6.6 min, 2.63–5.83 MPa, and 6.5–5.7, respectively.

The cell viability to gypsum (Gp) with different CT concentrations was similar to that of the control on day 1 but statistically different from that of Gp alone on day 3.

The ALP activity of SHED was significantly higher (p < 0.05) in CT- and BMP-2-containing materials than those in the control and Dycal at days 3 and 14.

The scanning electron microscopy (SEM) image revealed that flattened cells were distributed across and adhered to the material surface.

In conclusion, Gp-CT material shows promise as a potential material for direct pulp capping.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Subhi, Hasan& Reza, Fazal& Husein, Adam& Al Shehadat, Saaid Ayesh& Nurul, Asma-Abdullah. 2018. Gypsum-Based Material for Dental Pulp Capping: Effect of Chitosan and BMP-2 on Physical, Mechanical, and Cellular Properties. International Journal of Biomaterials،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1169576

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Subhi, Hasan…[et al.]. Gypsum-Based Material for Dental Pulp Capping: Effect of Chitosan and BMP-2 on Physical, Mechanical, and Cellular Properties. International Journal of Biomaterials No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1169576

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Subhi, Hasan& Reza, Fazal& Husein, Adam& Al Shehadat, Saaid Ayesh& Nurul, Asma-Abdullah. Gypsum-Based Material for Dental Pulp Capping: Effect of Chitosan and BMP-2 on Physical, Mechanical, and Cellular Properties. International Journal of Biomaterials. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1169576

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1169576