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Diagnosis of Alzheimer’s Disease Based on Structural MRI Images Using a Regularized Extreme Learning Machine and PCA Features
المؤلفون المشاركون
Lee, Sang-Woong
Lama, Ramesh Kumar
Gwak, Jeonghwan
Park, Jeong-Seon
المصدر
Journal of Healthcare Engineering
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-06-18
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Alzheimer’s disease (AD) is a progressive, neurodegenerative brain disorder that attacks neurotransmitters, brain cells, and nerves, affecting brain functions, memory, and behaviors and then finally causing dementia on elderly people.
Despite its significance, there is currently no cure for it.
However, there are medicines available on prescription that can help delay the progress of the condition.
Thus, early diagnosis of AD is essential for patient care and relevant researches.
Major challenges in proper diagnosis of AD using existing classification schemes are the availability of a smaller number of training samples and the larger number of possible feature representations.
In this paper, we present and compare AD diagnosis approaches using structural magnetic resonance (sMR) images to discriminate AD, mild cognitive impairment (MCI), and healthy control (HC) subjects using a support vector machine (SVM), an import vector machine (IVM), and a regularized extreme learning machine (RELM).
The greedy score-based feature selection technique is employed to select important feature vectors.
In addition, a kernel-based discriminative approach is adopted to deal with complex data distributions.
We compare the performance of these classifiers for volumetric sMR image data from Alzheimer’s disease neuroimaging initiative (ADNI) datasets.
Experiments on the ADNI datasets showed that RELM with the feature selection approach can significantly improve classification accuracy of AD from MCI and HC subjects.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lama, Ramesh Kumar& Gwak, Jeonghwan& Park, Jeong-Seon& Lee, Sang-Woong. 2017. Diagnosis of Alzheimer’s Disease Based on Structural MRI Images Using a Regularized Extreme Learning Machine and PCA Features. Journal of Healthcare Engineering،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1181052
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lama, Ramesh Kumar…[et al.]. Diagnosis of Alzheimer’s Disease Based on Structural MRI Images Using a Regularized Extreme Learning Machine and PCA Features. Journal of Healthcare Engineering No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1181052
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lama, Ramesh Kumar& Gwak, Jeonghwan& Park, Jeong-Seon& Lee, Sang-Woong. Diagnosis of Alzheimer’s Disease Based on Structural MRI Images Using a Regularized Extreme Learning Machine and PCA Features. Journal of Healthcare Engineering. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1181052
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1181052
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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