Antidiabetic Potential of Marine Brown Algae—a Mini Review
المؤلفون المشاركون
Peiris, L. Dinithi. C.
Gunathilaka, Thilina L.
Samarakoon, Kalpa
Ranasinghe, Pathmasiri
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-04-25
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Marine algae are an important source of bioactive metabolites in drug development and nutraceuticals.
Diabetes mellitus is a metabolic disorder and the third leading cause of death worldwide due to lifestyle changes associated with rapid urbanization.
Due to the adverse side effects of currently available antidiabetic drugs, search for an effective natural-based antidiabetic drug is important to combat diabetes and its complications.
Therefore, in lieu with herbal drug development, it is important to find the potential benefits of seaweeds for the management of type 2 diabetes as they are underexplored yet in Sri Lanka.
Among the marine seaweeds, natural bioactive compounds are abundant in brown algae with potentials in application as active ingredients in drug leads and nutraceuticals.
Bioactive secondary metabolites are derived from numerous biosynthetic pathways of marine algae which contribute to various chemical and biological properties.
Phlorotannins present in marine brown algae exhibited antidiabetic activities through different mechanisms such as the inhibitory effect of enzyme targets mainly by inhibiting the enzymes such as α-amylase, α-glucosidase, angiotensin-converting enzymes (ACE), aldose reductase, dipeptidyl peptidase-4, and protein tyrosine phosphatase 1B (PTP 1B) enzyme.
In addition, phlorotannins derived from brown algae have the ability to reduce diabetic complications.
Hence, the present review focuses on the different antidiabetic mechanisms of secondary bioactive compounds present in marine brown algae.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gunathilaka, Thilina L.& Samarakoon, Kalpa& Ranasinghe, Pathmasiri& Peiris, L. Dinithi. C.. 2020. Antidiabetic Potential of Marine Brown Algae—a Mini Review. Journal of Diabetes Research،Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1182863
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gunathilaka, Thilina L.…[et al.]. Antidiabetic Potential of Marine Brown Algae—a Mini Review. Journal of Diabetes Research No. 2020 (2020), pp.1-13.
https://search.emarefa.net/detail/BIM-1182863
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gunathilaka, Thilina L.& Samarakoon, Kalpa& Ranasinghe, Pathmasiri& Peiris, L. Dinithi. C.. Antidiabetic Potential of Marine Brown Algae—a Mini Review. Journal of Diabetes Research. 2020. Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1182863
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1182863
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر