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Outer Retinal Layers’ Thickness Changes in relation to Age and Choroidal Thickness in Normal Eyes
المؤلفون المشاركون
Kamal Abdellatif, Mona
Abdelmaguid Mohamed Elzankalony, Yasser
Abdelmonsef Abdelhamid Ebeid, Ahmed
Mohamed Ebeid, Weam
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-07-31
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Purpose.
To identify and correlate age-related changes in outer retinal layers’ thickness and choroidal thickness (CT) in the normal eyes using spectral-domain optical coherence tomography (SD-OCT) and to investigate factors affecting these changes.
Study Design.
Observational cross-sectional study.
Subjects and Methods.
We studied 125 healthy Egyptians between 20 and 79 years old.
Patients were divided into 3 groups: group 1 (20–40 years), group 2 (40–60 years), and group 3 (>60 years).
All patients had full ophthalmic examination.
SD-OCT was done to measure the 9 ETDRS macular grid sectors of retinal pigment epithelium and photoreceptor outer segment (RPE-OS), outer nuclear layer and photoreceptor inner segment (ONL-IS), and choroidal thickness (CT) (by enhanced depth imaging).
Results.
RPE-OS was significantly thinner in group 3 than in the other 2 groups (central: P<0.001).
Moreover, the 3 groups were significantly different from each other regarding the CT (central: P<0.001); significant thinning was noticed in the choroid with age.
The 3 groups did not show significant difference concerning the ONL-IS thickness.
RPE-OS and CT showed statistically significant negative correlation with age (central RPE-OS: r = −0 C.345, P<0.001, and central CT: r = −0.725, P<0.001) while ONL-IS showed statistically nonsignificant correlation with age (central ONL-IS: r = −0.08, P=0.376).
Multiple regression analysis revealed that the most important determinant of central 1 mm RPE-OS thickness in this study was age (β = −0.087, P=0.010) rather than choroidal thinning (β = 0.001, P=0.879).
Conclusion.
RPE-OS layer thickness shows significant thinning with increasing age, and with decrease in CT, however, age is the most determinant factor of this thinning.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kamal Abdellatif, Mona& Abdelmaguid Mohamed Elzankalony, Yasser& Abdelmonsef Abdelhamid Ebeid, Ahmed& Mohamed Ebeid, Weam. 2019. Outer Retinal Layers’ Thickness Changes in relation to Age and Choroidal Thickness in Normal Eyes. Journal of Ophthalmology،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1185130
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kamal Abdellatif, Mona…[et al.]. Outer Retinal Layers’ Thickness Changes in relation to Age and Choroidal Thickness in Normal Eyes. Journal of Ophthalmology No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1185130
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kamal Abdellatif, Mona& Abdelmaguid Mohamed Elzankalony, Yasser& Abdelmonsef Abdelhamid Ebeid, Ahmed& Mohamed Ebeid, Weam. Outer Retinal Layers’ Thickness Changes in relation to Age and Choroidal Thickness in Normal Eyes. Journal of Ophthalmology. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1185130
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1185130
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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