Green Synthesis of Silver Nanoparticles Using Grewia optiva Leaf Aqueous Extract and Isolated Compounds as Reducing Agent and Their Biological Activities

المؤلفون المشاركون

Hanif, Muhammad
Mahmood, Hafiz Majid
Bari, Ahmed
Naz, Sumaira
Ullah, Riaz
Zahoor, Muhammad
Nazir, Nausheen
Batiha, Gaber El-Saber
Iftikhar, Muhammad

المصدر

Journal of Nanomaterials

العدد

المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-10، 10ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2020-10-24

دولة النشر

مصر

عدد الصفحات

10

التخصصات الرئيسية

الكيمياء
هندسة مدنية

الملخص EN

In this study, an attempt was made to synthesize silver nanoparticles (Ag-NPs) using Grewia optiva leaf extract and isolated compounds.

The bioreductant capacity of Grewia optiva leaf extract for the synthesis of Ag-NPs was assessed using various confirmatory techniques like thermogravimetric analysis (TGA), particle size analysis (PSA), energy-dispersive X-ray (EDX), X-ray diffraction (XRD) analysis, scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), and UV-Visible spectroscopy.

The presence of various bioactive compounds in leaf aqueous extract was confirmed through HPLC analysis, and 8 compounds were identified among the different peaks present in the chromatogram.

Biopotencies like antioxidant, antibacterial, and effect on hair growth were determined for extract and NPs.

Antioxidant capacities were assessed through standard ABTS and DPPH methods.

The antibacterial potential was evaluated in terms of zone of inhibition, minimum bactericidal concentration, and minimum inhibitory concentration of the Ag-NPs and the leaf extract against selected strains of bacteria, whereas the effect on growth of rabbit hair was studied through topical treatment for a specific period of time.

Better antibacterial and DPPH and ABTS free radical inhibition was observed for the formulated Ag-NPs as compared to leaf extract.

The previously isolated eight compounds from this plant’s chloroform and ethyl acetate extracts were also tested for their bioreductant capacities.

Out of them, the highest amount of precipitates was obtained with compound VII ((2,5-dihydroxyphenyl)-3′,6′,8′-trihydroxyl-4H-chromen-4′-one).

The study implies that the biogenically engineered nanoscale particles could have promising biological activities in comparison to parental extract and they need to be investigated further as potential therapeutic agents to be used as antibacterial and antioxidant agents and for hair growth enhancement.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Iftikhar, Muhammad& Zahoor, Muhammad& Naz, Sumaira& Nazir, Nausheen& Batiha, Gaber El-Saber& Ullah, Riaz…[et al.]. 2020. Green Synthesis of Silver Nanoparticles Using Grewia optiva Leaf Aqueous Extract and Isolated Compounds as Reducing Agent and Their Biological Activities. Journal of Nanomaterials،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1188611

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Iftikhar, Muhammad…[et al.]. Green Synthesis of Silver Nanoparticles Using Grewia optiva Leaf Aqueous Extract and Isolated Compounds as Reducing Agent and Their Biological Activities. Journal of Nanomaterials No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1188611

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Iftikhar, Muhammad& Zahoor, Muhammad& Naz, Sumaira& Nazir, Nausheen& Batiha, Gaber El-Saber& Ullah, Riaz…[et al.]. Green Synthesis of Silver Nanoparticles Using Grewia optiva Leaf Aqueous Extract and Isolated Compounds as Reducing Agent and Their Biological Activities. Journal of Nanomaterials. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1188611

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1188611