Fixed Regimen Treatment in Unselected Naïve Patients Cohort with Neovascular Age-Related Macular Degeneration
المؤلفون المشاركون
Casaroli-Marano, Ricardo P.
Bernal-Morales, Carolina
Chamorro-López, Lillian
Dotti-Boada, Marina
Figueroa-Vercellino, Juan P.
Alforja, Socorro
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-11-21
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
The current treatment of neovascular age-related macular degeneration (nAMD) generates an excessive care pressure in the public health system.
The search for a satisfactory treatment regimen, whose anatomical and functional stability may be achieved, is a challenge and a goal to be reached.
We analyzed the outcomes in a patient cohort under fixed regimen treatment with intravitreal aflibercept (IVA).
A retrospective study, with at least 1-year follow-up, in consecutive treated unselected naïve patients was carried out.
Standard protocol was performed and evaluated at baseline, month 4 (after loading dose, LD), and month 12 (after fixed bimonthly regimen).
One hundred six patients (123 eyes) aged 80.3 ± 7.7 years were included, receiving 6.8 ± 0.7 IVA.
Visual acuity gain after LD was 5.5 ± 12.0 letters (p<0.0001).
At month 12, 23 eyes (18.7%) gained ≥15 letters and 58 (47.1%) had best-corrected visual acuity ≥20/40 (70 letters).
The improvement in visual acuity was lower in patients with polypoidal choroidal vasculopathy (+4.9 ± 18.1 letters; p = 0.2544) and somewhat higher in patients with retinal angiomatous proliferation (+5.4 ± 12.3 letters; p=0.0373).
Dry macula was present in only 9.8% of cohort at baseline vs.
69.7% at month 12 (p<0.0001).
Atrophy was the most observed complication and related to the elderly patients.
The average of follow-up visits was 3 ± 0.5.
Functional and anatomical improvement were observed with IVA in a fixed bimonthly regimen treatment after LD, with results maintained up to one year with a good compliance.
The fixed bimonthly regimen optimized patient management and logistic issues.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Casaroli-Marano, Ricardo P.& Bernal-Morales, Carolina& Chamorro-López, Lillian& Dotti-Boada, Marina& Figueroa-Vercellino, Juan P.& Alforja, Socorro. 2020. Fixed Regimen Treatment in Unselected Naïve Patients Cohort with Neovascular Age-Related Macular Degeneration. Journal of Ophthalmology،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1189805
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Casaroli-Marano, Ricardo P.…[et al.]. Fixed Regimen Treatment in Unselected Naïve Patients Cohort with Neovascular Age-Related Macular Degeneration. Journal of Ophthalmology No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1189805
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Casaroli-Marano, Ricardo P.& Bernal-Morales, Carolina& Chamorro-López, Lillian& Dotti-Boada, Marina& Figueroa-Vercellino, Juan P.& Alforja, Socorro. Fixed Regimen Treatment in Unselected Naïve Patients Cohort with Neovascular Age-Related Macular Degeneration. Journal of Ophthalmology. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1189805
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1189805
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر