PPARγ and Its Role in Cardiovascular Diseases

المؤلفون المشاركون

Chandra, Mini
Miriyala, Sumitra
Panchatcharam, Manikandan

المصدر

PPAR Research

العدد

المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-10، 10ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2017-01-24

دولة النشر

مصر

عدد الصفحات

10

التخصصات الرئيسية

الأحياء

الملخص EN

Peroxisome proliferator-activated receptor Gamma (PPARγ), a ligand-activated transcription factor, has a role in various cellular functions as well as glucose homeostasis, lipid metabolism, and prevention of oxidative stress.

The activators of PPARγ are already widely used in the treatment of diabetes mellitus.

The cardioprotective effect of PPARγ activation has been studied extensively over the years making them potential therapeutic targets in diseases associated with cardiovascular disorders.

However, they are also associated with adverse cardiovascular events such as congestive heart failure and myocardial infarction.

This review aims to discuss the role of PPARγ in the various cardiovascular diseases and summarize the current knowledge on PPARγ agonists from multiple clinical trials.

Finally, we also review the new PPARγ agonists under development as potential therapeutics with reduced or no adverse effects.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Chandra, Mini& Miriyala, Sumitra& Panchatcharam, Manikandan. 2017. PPARγ and Its Role in Cardiovascular Diseases. PPAR Research،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1197266

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Chandra, Mini…[et al.]. PPARγ and Its Role in Cardiovascular Diseases. PPAR Research No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1197266

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Chandra, Mini& Miriyala, Sumitra& Panchatcharam, Manikandan. PPARγ and Its Role in Cardiovascular Diseases. PPAR Research. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1197266

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1197266