EPR Spectroscopic Examination of Different Types of Paramagnetic Centers in the Blood in the Course of Burn Healing

المؤلفون المشاركون

Ramos, Paweł
Pilawa, Barbara
Kasperczyk, Janusz
Olczyk, Krystyna
Krzyminiewski, Ryszard
Dobosz, Bernadeta
Stojko, Mateusz
Ivanova, Diana
Stojko, Jerzy
Olczyk, Pawel
Komosinska-Vassev, Katarzyna

المصدر

Oxidative Medicine and Cellular Longevity

العدد

المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2019-06-19

دولة النشر

مصر

عدد الصفحات

8

التخصصات الرئيسية

الأحياء

الملخص EN

The multicomponent electron paramagnetic resonance spectra of the blood during healing of skin burned wounds treated with a new generation biodegradable dressings containing poly(lactide-co-glycolide) were analysed.

The evolution of different types of paramagnetic centers in the blood with time of healing was determined.

The EPR spectra of the blood samples at 230 K temperature were measured at 1, 10, and 21 days after burning of the pig skin.

The EPR lines of the following paramagnetic centers: the high-spin Fe3+ in methemoglobin (line I), high-spin Fe3+ in transferrin (line II), and Cu2+ in ceruloplasmin and free radicals (line III) were observed in the X-band (9.3 GHz) spectra of the blood.

The multicomponent structure of the EPR spectra of the tested blood samples depended on the time of the healing of the burned wounds.

The amount of the high-spin Fe3+ in methemoglobin (line I) in the blood decreased after 21 days of the healing of the burned wounds.

The amount of the high-spin Fe3+ in transferrin (line II) slightly increased after 21 days of therapy with the basis.

The amount of Cu2+ in ceruloplasmin and free radicals (line III) in the blood was very high after 10 days of therapy.

At the first day of the healing of the burned wounds, the highest amount of the high-spin Fe3+ in methemoglobin (line I), the relatively lower amounts of the high-spin Fe3+ in transferrin (line II), and Cu2+ in ceruloplasmin and free radicals (line III) existed in the blood.

In the medium phase (after 10 days) of the healing of the burned wounds, the extremely higher amounts of Cu2+ in ceruloplasmin and free radicals (line III) appeared in the blood.

In the last phase (after 21 days), only the low differences between the amounts of the high-spin Fe3+ in methemoglobin (line I), the high-spin Fe3+ in transferrin (line II), and Cu2+ in ceruloplasmin and free radicals (line III) were observed.

The present study may serve as a starting point for the development of a new technique for monitoring molecular complexes containing iron Fe3+ (methemoglobin, transferrin) or copper Cu2+ ions (ceruloplasmin) and free radicals in the blood during wound healing.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Komosinska-Vassev, Katarzyna& Olczyk, Pawel& Kasperczyk, Janusz& Pilawa, Barbara& Krzyminiewski, Ryszard& Dobosz, Bernadeta…[et al.]. 2019. EPR Spectroscopic Examination of Different Types of Paramagnetic Centers in the Blood in the Course of Burn Healing. Oxidative Medicine and Cellular Longevity،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1205172

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Komosinska-Vassev, Katarzyna…[et al.]. EPR Spectroscopic Examination of Different Types of Paramagnetic Centers in the Blood in the Course of Burn Healing. Oxidative Medicine and Cellular Longevity No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1205172

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Komosinska-Vassev, Katarzyna& Olczyk, Pawel& Kasperczyk, Janusz& Pilawa, Barbara& Krzyminiewski, Ryszard& Dobosz, Bernadeta…[et al.]. EPR Spectroscopic Examination of Different Types of Paramagnetic Centers in the Blood in the Course of Burn Healing. Oxidative Medicine and Cellular Longevity. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1205172

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1205172