Impaired Geotaxis as a Novel Phenotype of Nora Virus Infection of Drosophila melanogaster
المؤلفون المشاركون
Carlson, Kimberly A.
Rogers, Abigail
Towery, Lesley
McCown, Amanda
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-07-30
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Nora virus (NV) is a picorna-like virus that contains a positive-sense, single-stranded RNA genome.
The virus infects Drosophila melanogaster with no known characterized phenotype.
In this study, geotaxis assays and longevity analyses were used to determine if Nora virus infection affects D.
melanogaster’s locomotor ability.
In addition, Drosophila C virus (DCV), a well-characterized D.
melanogaster virus, was used as a positive control, as it has previously shown a locomotor defect in infected flies.
Stocks infected with NV (NV+) and DCV (DCV+) and virus-free (NV-/DCV-) stocks were established.
Over a 3-year period, approximately 2,500 virgin female flies were tested for geotaxis and longevity using Kaplan–Meier analyses, as well as the Cox Proportional Hazards regression for survivorship.
There was a significant decrease in the geotaxis when the D.
melanogaster flies were infected with Nora virus compared to uninfected controls, but no difference was found between DCV+ and NV+ trials.
There were not significant differences in longevity between the three groups.
This is the first time that a phenotype has been recorded in association with Nora virus infection.
Overall, the data demonstrate that geotaxis dysfunction may be a phenotypic hallmark of Nora virus infection.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rogers, Abigail& Towery, Lesley& McCown, Amanda& Carlson, Kimberly A.. 2020. Impaired Geotaxis as a Novel Phenotype of Nora Virus Infection of Drosophila melanogaster. Scientifica،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1208121
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rogers, Abigail…[et al.]. Impaired Geotaxis as a Novel Phenotype of Nora Virus Infection of Drosophila melanogaster. Scientifica No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1208121
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rogers, Abigail& Towery, Lesley& McCown, Amanda& Carlson, Kimberly A.. Impaired Geotaxis as a Novel Phenotype of Nora Virus Infection of Drosophila melanogaster. Scientifica. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1208121
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1208121
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر