Tristemma hirtum and Five Other Cameroonian Edible Plants with Weak or No Antibacterial Effects Modulate the Activities of Antibiotics against Gram-Negative Multidrug-Resistant Phenotypes
المؤلفون المشاركون
Kuete, Victor
Mbaveng, Armelle T.
Manekeng, Hermione T.
Wamba, Brice E. N.
Nayim, Paul
Nguenang, Gaëlle S.
Fankam, Aimé G.
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-03-22
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
In order to contribute to the fight against infectious diseases, the in vitro antibacterial activity and the antibiotic-potentiating effects of Tristemma hirtum and five other Cameroonian edible plants have been evaluated against Gram-negative multidrug-resistant (MDR) phenotypes.
The microdilution method was used to evaluate the bacterial susceptibility of the extracts and their combination to common antibiotics.
The phytochemical screening of the extracts was carried out according to standard methods.
Phytochemical analysis of the extracts revealed the presence of alkaloids, triterpenes, steroids, and polyphenols, including flavonoids in most of the tested extracts.
The entire tested extracts showed moderate (512 μg/mL ≤ MIC ≤ 2048 μg/mL) to weak (MIC > 2048 μg/mL) antibacterial activities against the tested bacteria.
Furthermore, extracts of leaf of Tristemma hirtum and pericarps of Raphia hookeri (at their MIC/2 and MIC/4) strongly potentiated the activities of all antibiotics used in the study, especially those of chloramphenicol (CHL), ciprofloxacin (CIP), kanamycin (KAN), and tetracycline (TET) against 70% (7/10) to 100% (10/10) of the tested MDR bacteria, with the modulating factors ranging from 2 to 128.
The results of this study suggest that extracts from leaves of Tristemma hirtum and pericarps of Raphia hookeri can be sources of plant-derived products with antibiotic modifying activity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nguenang, Gaëlle S.& Mbaveng, Armelle T.& Fankam, Aimé G.& Manekeng, Hermione T.& Nayim, Paul& Wamba, Brice E. N.…[et al.]. 2018. Tristemma hirtum and Five Other Cameroonian Edible Plants with Weak or No Antibacterial Effects Modulate the Activities of Antibiotics against Gram-Negative Multidrug-Resistant Phenotypes. The Scientific World Journal،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1215659
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nguenang, Gaëlle S.…[et al.]. Tristemma hirtum and Five Other Cameroonian Edible Plants with Weak or No Antibacterial Effects Modulate the Activities of Antibiotics against Gram-Negative Multidrug-Resistant Phenotypes. The Scientific World Journal No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1215659
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nguenang, Gaëlle S.& Mbaveng, Armelle T.& Fankam, Aimé G.& Manekeng, Hermione T.& Nayim, Paul& Wamba, Brice E. N.…[et al.]. Tristemma hirtum and Five Other Cameroonian Edible Plants with Weak or No Antibacterial Effects Modulate the Activities of Antibiotics against Gram-Negative Multidrug-Resistant Phenotypes. The Scientific World Journal. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1215659
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1215659
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر