Evaluation of diagnostic value of SPECT-CT imaging in post-radioiodine therapy in thyroid cancer
المؤلفون المشاركون
Jain, Anjali
al-Hatimi, Asma
Mittal, Alok Kumar
Husayn, Samir
المصدر
Sultan Qaboos University Medical Journal
العدد
المجلد 22، العدد 1 (28 فبراير/شباط 2022)، ص ص. 74-81، 8ص.
الناشر
جامعة السلطان قابوس كلية الطب و العلوم الصحية
تاريخ النشر
2022-02-28
دولة النشر
سلطنة عمان
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objectives: This study aimed to investigate the value of single photon emission computed tomography/ computed tomography (SPECT/CT) imaging in well-differentiated thyroid cancer (DTC) after radioiodine (I-131) ablation/therapy for clinical staging and risk stratification.
It also aimed to determine whether SPECT/CT would change the management plan or predict the clinical outcomes of DTC patients.
Methods: A total of 78 DTC patients underwent first post radioiodine therapy “Whole body iodine-131 scintigraphy (WBS) along with SPECT/CT” at the Department of Radiology and Molecular imaging, Sultan Qaboos University Hospital, Muscat, Oman, between January 2014 and August 2017.
Differences between WBS and SPECT/CT, change in clinical staging, risk stratification and management were recorded.
The clinical outcome at 6–12 months was recorded.
A generalised McNemar test was used to assess disagreement between WBS and SPECT/CT.
Results: According to the American Thyroid Association (ATA) risk stratification, the sample showed low (35.8%), intermediate (53.8%) and high-risk groups (10.2%) on WBS, which changed to 44.8%, 38.4% and 16.6%, respectively, on SPECT/CT imaging.
Overall change in risk stratification was noted in 16.7% and TNM stage in 11.5% of patients after SPECT/CT imaging.
SPECT/CT changed the therapeutic plan and clinical outcome in 19.2% of patients.
Conclusion: SPECT/CT allows better detection and characterisation of metastatic lymph nodes and distant metastasis in DTC patients compared to WBS imaging alone.
It alters TNM staging, ATA risk classification and management in a significant number of patients.
It is recommended that SPECT/ CT should be done routinely along with WBS in well-differentiated thyroid carcinoma.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Hatimi, Asma& Jain, Anjali& Mittal, Alok Kumar& Husayn, Samir. 2022. Evaluation of diagnostic value of SPECT-CT imaging in post-radioiodine therapy in thyroid cancer. Sultan Qaboos University Medical Journal،Vol. 22, no. 1, pp.74-81.
https://search.emarefa.net/detail/BIM-1343802
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Hatimi, Asma…[et al.]. Evaluation of diagnostic value of SPECT-CT imaging in post-radioiodine therapy in thyroid cancer. Sultan Qaboos University Medical Journal Vol. 22, no. 1 (Feb. 2022), pp.74-81.
https://search.emarefa.net/detail/BIM-1343802
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Hatimi, Asma& Jain, Anjali& Mittal, Alok Kumar& Husayn, Samir. Evaluation of diagnostic value of SPECT-CT imaging in post-radioiodine therapy in thyroid cancer. Sultan Qaboos University Medical Journal. 2022. Vol. 22, no. 1, pp.74-81.
https://search.emarefa.net/detail/BIM-1343802
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references : p. 80-81
رقم السجل
BIM-1343802
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر