مداواة البكتيريا المقاومة للمضادات الحيوية Clostridium difficile بزراعة الفضلات البشرية FMT : دراسة طبية فقهية

الملخص EN

This study aims to describe and identify the fecal microbiota transplant (FMT) treatment for clostridium difficile infection in Islamic jurisprudence point of view.

this infection is a serious condition, despite the fact of low infection rate in the middle east countries, it has high mortality rate for hospitalized patients with pseudomembranous colitis.

the recurrence and resistance to multiple antibiotics cases can be treated with invasive method which inserting microbiota using fecal transplant material.

this study is divided into three main parts : introduction, sub-sections and a conclusion.

the introduction is divided into two sub-headings ; 1.

clostridium difficile overview and 2.

diagnostic and treatment protocols.

the sub-section is the Islamic juristic study for the treatment with FMT which is divided into two subheadings.

to conclude, this infection is usually treated with antibiotics for long period but the sever and recurrent infection can be treated effectively with FMT.

the FMT is invasive method which includes many forms each has its own specific fatwa*.

all treatment protocols are considered permitted in Islam, however, the treatment with human and animal remains is not permitted.

FMT treatment by rectal and colonoscopy route of administration are permitted based on the condition and burden of the critical and unresponsiveness to antibiotics treatment situation.

it is better to not start FMT before using antibiotics approach and be certain that antibiotics are not effective in the sever condition.

we recommend that FMT protocol must be studied clinically and by Islamic jurisprudence in a wider range to weigh between the risks and benefits for FMT approach.