تقييم مشعر اختلاف حجم كريات الدم الحمراء عند مرضى الاعتلال الكلوي التالي للداء السكري النمط الثاني

الملخص EN

Objective : diabetic nephropathy (DN) is an important cause of morbidity and mortality of diabetes mellitus (DM) patients.

Inflammation has a pivotal role in DN pathogenesis.

red cell distribution width (RDW), is a current parameter which has been supposed to be a marker of ineffective erythropoiesis depending on chronic inflammation and neurohumoral activation.

we aimed to compare levels RDW, which is a marker of inflammation, between DM patients with and without diabetic nephropathy.

methods: eighty-four type 2 DM patients (50 diabetic nephropathy patients and 34 patients without diabetic nephropathy).

All clinical and laboratory data including urea, creatinine, hemogram, fasting blood glucose, lipid profile were recorded.

Results : RDW values of diabetic nephropathy patients was significantly higher than those of patients without diabetic nephropathy (p=0.002).

RBC, MCV, and duration of diabetes were statistically significantly different(p=0.04, 0.01, and 0.02 respectively), whereas BMI, fasting blood glucose, triglycerides, total cholesterol levels were not statistically significantly different (p=0.87, 0.91, 0.64, and 0.42 respectively).

conclusions : as an easy and convenient routine examination, RDW may provide better clinical guidance along with other important indices.