Facile, single-pot preparation of nanoporous SiO₂ particles (carrier)‎ with AgNPs at core and crust for controlled disinfectant release

الملخص EN

This study demonstrates a novel, facile and one-pot approach to synthesize silica nanoparticles with silver at core and crust (SiNP-AgCC).

A modified Stöber method was used to make SiNP-AgCC.

A significant reduction in the size of SiO₂ nanoparticles was seen, with 2-5 nm AgNPs being uniformly distributed on the surface and 10-20 nm AgNPs in the center.

A typical mesoporous SiO₂ particle (SiNP) produced using the Stöber method was transformed to nanoporous SiO₂ by this modified Stöber method.

Nanoporous SiO₂ particles with silver in the center are advantageous for slow and consistent Ag release, which was confirmed by Ag+ ion release test.

Antibacterial activities of the samples were tested to evaluate the disinfection performance of the samples on gram-negative bacteria (Escherichia coli) using disk diffusion and the LB-agar method.

SiNP-AgCC showed prolonged silver release for more than 20 days and improved antibacterial properties even after five days of incubation.