التغيرات النسيجية المرضية في كبد و كلى الفئران البضاء المتغذية على ألبان ملوثة بالأفلاتوكسين

الملخص EN

The daily oral administration of contaminated milk with AFM1 (0.11ng/0.1ml milk/day) for 6 months caused sever damage in both liver and kidney tissue of albino mice.

There is apoptotic death of liver cells , appearance of intra nuclear inclusions , nuclear enlargement (megakaryocytes) or binucleated cells, which could be considered as precancerous features.

On the other hand there was atrophy of renal corpuscles, and lining cells of renal tubules with presence of protenious cast within their Lumina.

Some cells show vacuolation.

Vascular congestion was also observed.