تقييم التأثيرات العلاجية لمركب الفايسين و عقار الألبندازول تجاه طفيلي الأكياس العدرية Echinococcus granulosus L. داخل و خارج الجسم الحي

الملخص EN

The present study is included isolation and identification of vicine from Helianthus annus L.

and Hibiscus sabdariffa L and evaluation activity of it and albendazole in killing of protoscolices isolation from sheep liver In vitro , also studying pathogenic effects on the liver and kidney and blood indicators beside of activity of vicine and albendazole on hydatid cyst number and volume in vivo added to toxicity effects for it.

This study appeared that vicine which extract from H.

sabdariffa.

has more activity in killing of protoscolices in vitro compared with the same compound which extracted from H.

annus beside of albendazole.

This dosage causes histological change in mice for liver represent as inflammation response variance in severity ; where as it was less in mice which treatment with vicine from H.

sabdariffa compared with the same compound which extracted from H.

annus beside of albendazole.

Also appearance histological change on the kidney as hemorrhage and necrosis in kidney tubules.

Also causes vicine from H.

sabdariffa decrease in hydatid cyst number and volume compared with the same compound which extracted from H.

annus beside of albendazole.

In addition appearance decrease in hemoglobin.