توصيف زيوت نبات المريمية Salvia officinalis و دراسة فعاليتها المضادة للتطفير الناتج عن الدورسبان

الملخص EN

This study was conducted in an attempt to characterize the fixed and volatile oils of Salvia officinalis L.

plant , as well as to detect the mutagenic effect of insecticide Dursban and its inhibition using these oils.

The oils were characterized using TLC and GC-MS.

The latter showed the presence of ten components in fixed oil (Nonane , Octane , Methyl salicyate , Tetradecanoic acid, Tridecanoic acid , Benzoic acid , Benzyl benzoate , Pentadecanoic acid, Heptadecanoic acid and 9- Octadecanoic acid) and fifteen components in volatile oil (Eucalyptol , Alpha-Terpinol , 1,6 –Octadien – 3- o1, Camphor, 2H-Inden-2-one , Naphthalene, Gamma-Terpinol , Trans – beta- Terpinyl butanoate, Isobornyl , Bornyl acetate , Isobornyl acetate , Caryophyllene, Isocaryophllene , Globulol and Ledol).

The Dursban mutagenic effects of different serial concentrations (0.03 , 0.04 , 0.06 , 0.08 and 0.12 μg / ml) on both the mitotic index (MI) and chromosomal aberrations for the root tips of the onion cells were studied.

Results of this test was revealed that the Dursban had a significant effects , and this was expressed by reduction of MI and create several aberrations such as sticky , bridges , breaks , fragments , clumping , disturbance and lagging chromosomes.

The medical oily extracts (1.25 μ1/ml) caused a reduction in the insecticide's mutagenic effect , and this was expressed through their inhibitory effects by increasing the MI to (9.90 , 13.

15 and 14.18) and (12.04 , 15.62 and 16.02) for both fixed and volatile oils , respectively.Beside that , they shared in the reduction of the chromosomal aberrations in the onion root cells.