دراسة سريرية لإنزيم مايلوبيروكسيديز و بعض المتغيرات الكيموحياتية في مرضى داء السكر

الملخص EN

The research included a clinical studying of Myeloperoxidase enzyme and some biochemical parameters in serum.

The normal value of Myeloperoxidase activity in control group was (30.27 U/ml) for both sexes in age group (15-77 year).

The results showed that Myeloperoxidase activity in the serum of control group was not affected by sex and marital status, while it was affected by age, smoke and body mass index.

The study also showed a significant decrease in serum Myeloperoxidase activity of Diabetes Mellitus patients group (19.17 U/ml) for both sexes at in age group (31-80 year) comparison with control, and the enzyme activity in serum of patients group was not affected by sex, marital status and type of disease, while it was affected by age, smoke and body mass index.

The results indicated a significant decrease in serum Myeloperoxidase activity in type Ι, type Π Diabetes Mellitus male in comparison with control male, and enzyme activity in type Ι, type Π Diabetes Mellitus female in comparison with control female.

Also the results showed a significant decrease in enzyme activity in age groups of type Ι, type Π patients in comparison with age groups of control, so that in comparison the body mass index for type Ι patients with control.

The results also predicted a significant decrease in serum Myeloperoxidase activity in type Ι, type Π Diabetes Mellitus smokers in comparison control smokers, and nonsmokers in comparison control nonsmokers.

The study also showed a significant increase in the level of Glucose, Total Cholesterol and Low Density lipoprotein, while a significant decrease in the level of Total protein, Albumin, Globulin and High Density lipoprotein in serum of type Ι Diabetes Mellitus patients in comparison control.

Also noticed a significant increase in the level of Glucose, Triglyceride, Total Cholesterol, Low Density lipoprotein, Very Low Density lipoprotein, while a significant decrease in the level of Total protein, Albumin, Globulin and High Density lipoprotein in serum of type Π Diabetes Mellitus patients in comparison control.