دراسة تغيرات الهرمونات التكاثرية المصاحبة لمتلازمة تكيس المبايض في النساء المصابات خلال السن الإنجابي في مدينة النجف

الملخص EN

There is interaction among hypothalamus gland, pituitary gland and ovary system in regulation of metabolic and reproductive function, this achieved by balance between hormonal stimulation and withdrawal of other hormone by feed back mechanism, any changes in this hormonal balance lead to reproductive diseases such as risk of PCOS in women of reproductive age.

Infertility, acne, hirsutism, obesity and galactorrhea are more common clinical symbiosis of PCOS, this study include measurement of level concentration of Gonadotrophine hormones which is (LH, FSH, progesterone and estrogen) to the patient's women with PCOS and comparing with normal control.

The results of this study referred to elevation of LH and FSH concentration, with lowered estrogen and progesterone concentration and this referes to ovarian failure in the reproductive function currenitly of patients with PCOS.

The result showed that there is a significant increase (p<0.05) in level LH in patients with PCOS as compared with control group.

While no significant differences (p>o.05) in level FSH but the result prove that a significant decrease (p<0.05) of levels of progesterone and estrogen in patients with PCOS in comparing with normal control and this study showed increased in patients women weight with PCOS compared with normal women weight .