التأثير الدوائي لعقار البندول Acetaminophen على المحتوى الوراثي في نقي عظم الفئران

الملخص EN

The uses of Acetaminophen is worldwide as pain killer and antipyretic properties on human body .But when there is misuse of that drug will result in negative adverse effects on different organs of body such as kidny and pancrease .This study throug uses of cytogenetic tests ( Chromosomal changes and miotic index ) in mouse bone morrow.

Use two doses of Acetaminophen drug (25 mg/ kg , 250mg/ kg) twise daily and after ingected during period ( 24,72,96 hr) it shows the following results: 1-suppresion in miotic index in cells of bone morrow and suppresion show more with incrase the concentration of drug .

2- increasing in Chromosomal abbration show more with incrase the concentration of drug .