Hyperthyroidism-Associated Insulin Resistance Is Not Mediated by Adiponectin Levels
المؤلفون المشاركون
Sun, Chun-Chin
Lee, Jenn-Kuen
Wang, Mei-Chun
Lu, Chih-Chen
Chu, Chih-Hsun
Chuang, Ming-Ju
Lam, Hing-Chung
المصدر
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-01-18
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
To evaluate the relationship between circulating adiponectin and insulin sensitivity in patients with hyperthyroid Graves' disease, we studied 19 adult patients with this disease and 19 age- and sex-matched euthyroid controls.
All hyperthyroid patients were treated with antithyroid drugs and were re-evaluated after thyroid function normalized.
Before antithyroid treatment, the adiponectin plasma concentrations were not different comparing with those in control group.
The adiponectin levels remained unchanged after treatment.
The homeostasis model assessment of insulin resistance (HOMA-IR) in hyperthyroid group was higher before treatment than after treatment.
There was no significant difference in serum glucose and insulin levels between hyperthyroid and control groups and in the hyperthyroid group before and after treatment.
BMI-adjusted adiponectin levels were not different among three groups.
On the other hand, BMI-adjusted insulin levels and HOMA-IR values were significantly decreased after management of hyperthyroidism.
Pearson's correlation revealed that insulin and HOMA-IR values positively correlated with triiodothyronine (T3) and free thyroxine (FT4) levels.
However, adiponectin did not correlate with T3, FT4, insulin, HOMA-IR and thyrotropin receptor autoantibody (TRAb) levels.
In conclusion, insulin resistance associated with hyperthyroidism is not mediated by the levels of plasma adiponectin.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chu, Chih-Hsun& Lam, Hing-Chung& Lee, Jenn-Kuen& Lu, Chih-Chen& Sun, Chun-Chin& Wang, Mei-Chun…[et al.]. 2011. Hyperthyroidism-Associated Insulin Resistance Is Not Mediated by Adiponectin Levels. Journal of Thyroid Research،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-453542
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chu, Chih-Hsun…[et al.]. Hyperthyroidism-Associated Insulin Resistance Is Not Mediated by Adiponectin Levels. Journal of Thyroid Research No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-453542
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chu, Chih-Hsun& Lam, Hing-Chung& Lee, Jenn-Kuen& Lu, Chih-Chen& Sun, Chun-Chin& Wang, Mei-Chun…[et al.]. Hyperthyroidism-Associated Insulin Resistance Is Not Mediated by Adiponectin Levels. Journal of Thyroid Research. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-453542
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-453542
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر